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Articles by S. Jayalakshmi
Total Records ( 2 ) for S. Jayalakshmi
  S. Jayalakshmi and S.P. Rajagopalan
  In a gene expression data matrix a bicluster is a submatrix of genes and conditions that exhibits a high correlation of expression activity across both rows and columns. The problem of locating the most significant bicluster has been shown to be NP-complete. Heuristic approaches such as Cheng and Church’s greedy node deletion algorithm have been previously employed. It is to be expected that stochastic search techniques such as evolutionary algorithms or simulated annealing might improve upon such greedy techniques. In this study we show that an approach based on modified simulated annealing is well suited to this problem and we present a comparative evaluation of simulated annealing and node deletion. We show that modified simulated annealing discovers more significant biclusters.
  R. Thavasi , S. Jayalakshmi , T. Balasubramanian and Ibrahim M. Banat
  The present study deals with the hydrocarbon degrading potential of a marine nitrogen fixing bacterium Azotobacter chroococcum isolated from Tuticorin harbor (Lat. 08o45`N; Long. 78o13`E). Degradation of crude oil (58%) and emulsification (D610) of waste motor oil (1.51), crude oil (1.43), pea nut oil (1.39), diesel (0.69), kerosene (0.81), Naphthalane (0.36), Anthracene (0.33) and xylene (0.42) indicated its potentiality in utilization of various hydrocarbons. Growth of Azotobacter chroococcum in a mineral medium with 0.5% crude oil as sole carbon source resulted maximum cell density at 96 h with an OD value of 0.333. At the end of 96 h, the cell count was 4.5x109 CFU mL-1 and 2.5 mg mL-1 of biomass. The biosurfactant production was found to be 1 mg mL-1 at 96 h. The total nitrogen fixed was 4.2 mg L-1. Two plasmids were found with molecular weight of 4788 and 2400 base pairs, respectively. Loss of biodegradation and biosurfactant production after plasmid curing was observed, which confirmed that, the biosurfactant production and biodegradation process were plasmid mediated. Results of the present study revealed the possibility of using marine nitrogen fixing hydrocarbon degrading bacteria and their biosurfactants in the abatement of marine oil pollution.
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