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Articles by Roseline Aliyu
Total Records ( 3 ) for Roseline Aliyu
  Roseline Aliyu , Donatien Gatsing and Kiri H. Jaryum
  The effect of the aqueous bark extract of Boswellia dalzielii (Burseraceae) on liver function was investigated using female Wistar rats. Graded concentrations of 0, 50, 100, 150 and 200 mg kg-1 body weight, of the aqueous bark extract of the plant sample were administered to the rats through gastric route and alkaline phosphatase, aspartate aminotransferase and alanine aminotransferase activities, total protein, albumin and bilirubin (total, conjugated and unconjugated) were determined in the serum. Phytochemical screening of the extract was also done. The extract of B. dalzielii was found to have no significant (p>0.05) effect on total protein and albumin content at the end of the 5 days treatment period. Total bilirubin and alkaline phosphatase activities did not show any significant (p>0.05) difference as compared with the control. However, unconjugated bilirubin was found to decrease significantly (p<0.05) with increased dose of extract. These results seem to suggest no damage to hepatocytes as a result of the exposure to the plant bark extract. Moreover the transaminase activities seem to corroborate this, since they decreased significantly (p<0.001) with increase in the concentration of extract, as compared to control values, suggesting that B. dalzielii bark extract may strengthen the liver. The presence of flavonoids further gives credence to the hepato-strengthening activity of B. dalzielii bark extract.
  Pierre C. Djemgou , Donatien Gatsing , Marguerite Kenmogne , Dieudonne Ngamga , Roseline Aliyu , Abiodun H. Adebayo , Pierre Tane , Bonaventure T. Ngadjui , Elisabeth Seguin and Godwin I. Adoga
  Phytochemical and biological investigation of the leaves of Cassia petersiana afforded four compounds including a new dihydroanthracenone (1), two known chromones (2,3), in addition to stigmasterol glucoside (4). The work was guided by the antisalmonellal activity of the extract and fractions. Compound 4 was found to be the active principle. The structures of the compounds were determined by combination of spectroscopic techniques, including 1H, 13C, DEPT, COSY, HMQC, HMBC, MS and IR.
  Donatien Gatsing , H. Ibrahim Garba , Roseline Aliyu , H. Abiodun Adebayo , P. Obekpa and I. Godwin Adoga
  The serum levels of some lysosomal enzymes-namely β-glucuronidase (EC 3.2.1.31), β-galactosidase (EC 3.2.1.23) and acid phosphatase (EC 3.1.3.2)-were measured in controls, pre-operative and post-operative nephroblastoma patients. β-glucuronidase activity showed a significant (p<0.05) increase before surgical intervention, followed by significant (p<0.05) decreases 24 h, 72 h and 7 days after operation. The activities of β-galactosidase and acid phosphatase showed no significant (p>0.05) changes before and after surgical intervention. These data indicate that nephroblastoma and surgery may have a marked effect on the serum levels of some lysosomal enzymes.
 
 
 
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