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Articles by R.A. El-Mergawi
Total Records ( 1 ) for R.A. El-Mergawi
  A.I. Al-Humaid , H.M. Mousa , R.A. El-Mergawi and A.M. Abdel-Salam
  Dates and camel milk have been reported to be used for prevention and treatment of various diseases in Arab countries. This study was designed to investigate the antioxidant activity of dates and camel milk, alone or as a mixture and their effect in lead acetate-poisoned rats. Lead was administered to rats in drinking water at a concentration of 0.6% to generate lipid peroxidation. Three cultivars of date fruits grown locally (Nabtat Ali, Sukkari and Rashudia) were tried when mixed individually with camel milk against lipid peroxidation generated by lead. Chemical composition of dates, camel milk and their mixture was determined. The organoleptic evaluation of palatability of date-camel milk mixtures was performed. Serum glucose, triglycerides and urea concentrations and activities of Aspartate Aminotransferase (AST/GOT), Alanine Aminotransferase (ALT/GPT) and Glutathione-S-Transferase (GST) enzymes were determined. Drinking water containing 0.6% lead acetate resulted in significant increase in serum glucose, triglycerides and urea concentrations, as well as increased activity of serum enzymes were investigated. It also reduced the serum activity of the antioxidant enzyme Glutathione-S-transferase. Mixing camel milk with date varieties of Rashudia, Nabtat Ali or Sukkari in ratio of 2:1 (v/w) increased milk antioxidant capacity by 49.2, 62.8 and 81.3%, respectively. It also reduced the elevated activities of serum enzymes, the concentration of urea and increased the activity of Glutathione-S-Transferase enzyme in poisoned rats. Mixtures of camel milk with the different cultivars of dates produced different beneficial effects. In conclusion, feeding a mixture of camel milk with dates seems to enhance the body defense against free radicals generated by the lead acetate poisoning mainly due to the high contents of phenolics and flavonoids in the mixture.
 
 
 
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