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Articles by O.A. Osonuga
Total Records ( 2 ) for O.A. Osonuga
  Y. Raji , I.O. Osonuga , O.S. Akinsomisoye , O.A. Osonuga and O.O. Mewoyeka
  Male Wister albino rats were exposed to artemether by gavage at dosages of 25, 50 and 75 mg kg-1 day-1 for 1, 2 and 3 days. The control groups received sterile water (control 1) and 5% ethanol (vehicle for artemether, control 2). The maximum volume injected in all groups was 0.5 mL. Rats administered the highest dose for three days were mated with female rats to determine the fertilizing capacity of their epididymal sperms and fertility status. Artemether significantly reduced (p<0.05) the progressive sperm motility, viability, sperm count and serum testosterone levels in dose and duration dependent manners, factors that may impair fertility. None of the untreated cohabited female rats got pregnant throughout the period of the study. These changes were restored in recovery experiments. The results suggest that artemether could induce reversible infertility in rats.
  Y. Raji , O.A. Osonuga , O.I Shittu , O.S. Akinsomisoye , V.A. Togun and Mistura O. Azeez
  A study of 542 randomly selected female students of the University of Ibadan and Ladoke Akintola University, Ogbomoso, both located in the southwestern Nigeria was carried out to determine the current menarcheal age and predicting factors influencing its onset. Mean age at menarche was found to be 13.66±1.82 years. 49.3% attained menarche between the ages of 13 and 14 years, 75.7% between 12 and 15 years, 8.1% at 16 while 6.1% had their first menstruation at age 11 years. There was a significant linear relationship (p = 0.004) between the age at menarche and body weight. The body surface area and height showed an insignificant inverse relationship with age at menarche. Socio-economic status of the parents had no influence on the age at menarche. Simple and multiple regression models for predicting age at menarche were derived from body weight, height and body surface area.
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