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Articles by Naresh Kumar Sood
Total Records ( 2 ) for Naresh Kumar Sood
  Anamika Gupta , Geeta Devi Leishangthem , Kuldip Gupta , Naresh Kumar Sood and Amarjit Singh
  Background: The present study was undertaken to investigate the expression of Th1 and Th2 cytokines and to correlate the expression of these cytokines with pathological changes associated with natural cases of specific and non-specific lymphadenopathies in bovines. Materials and Methods: The study included 32 cases of bovine lymphadenopathies presented for necropsy examination to the Department of Veterinary Pathology, GADVASU, Ludhiana, India. Samples from affected lymph nodes and visceral organs showing lesions were collected for cytology, histopathology, immunohistochemistry, ELISA and PCR. Results: There was variable expression of Th1 and Th2 cytokines in specific and non-specific lymphadenopathies in bovines. In lymphoma the expression of both Th1 and Th2 cytokines was decreased. There was increased expression of IFN-γ in bovine tuberculosis and strong IL-10 expression in Johne’s disease. In non-specific conditions, there was continuation of both Th1 and Th2 responses in acute lymphadenitis, along with increased Th2 expression in cases of hyperplasia, hemorrhagic and chronic lymphadenitis. Conclusion: The present study concluded that analysis of cytokine expression and pathological lesions in the lymph nodes of bovines are of paramount importance in diagnosis of specific and non-specific lymphadenopathies.
  Showkat Ahmad Shah , Naresh Kumar Sood and Srinivasa Rao Tumati
  Incidence of severe anemia due to babesiosis in dogs resulting in death in a short time of illness is on the increase in Punjab, during last few decades due to introduction of exotic breeds like Grey Hound, German shepherd, Doberman, Labrador and others. In the present study the hematological and biochemical changes in blood samples obtained from 4 dogs naturally infected with Babesia were evaluated. The dogs were presented to the Department of Veterinary Clinical Services Complex, GADVASU, Ludhiana from August 2008 to April 2009. The evaluation included Hemoglobin (Hb), Red Blood Cell count (RBC), Packed Cell Volume (PCV), Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin Concentration (MCHC), leucocyte counts, platelet counts and reticulocyte counts. The serum biochemistry included Blood Urea Nitrogen (BUN), creatinine, total protein, albumin, bilirubin, Aspartate amino Transferase (AST), Alanine amino Transferase (ALT), Alkaline Phosphatase (ALP), The hematological findings in most of these dogs were normocytic normochromic anemia and thrombocytopenia. The total and differential leukocyte counts were not specific. Biochemical values were within normal ranges but serum biochemistry varied for each dog. This study indicated that Babesia infection in dogs apparently caused anemia and thrombocytopenia, while other clinical values did not change.
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