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Articles by Mohamed Shahen
Total Records ( 2 ) for Mohamed Shahen
  Zhiming Shu , Akhtar Hussain Shar , Mohamed Shahen , He Wang , Mahmoud Alagawany , Mohamed E. Abd El-Hack , Shahmir Ali Kalhoro , Muhammad Rashid and Piar Ali Shar
  Globally the cardiovascular disease (CVDs) and coronary heart disease (CHD) are main cause of death. Ginkgo biloba is one of the oldest plants in the world, originating in China, science is known as the "living fossil". Ginkgo biloba leaves extract (GBLE) is a bioactive substance extracted from the Ginkgo biloba, the main active ingredients of Ginkgo flavonoids and ginkgolide compound, three or four, one of the most important Ginkgo biloba leaves extract is widely used as a drug or food additive in more than 130 countries. Thousands of years ago Asian and other region was use the traditional Chinese medicine (TCM), they verified some effective disorders. The medicinal uses of Ginkgo biloba have been widely used for various disease including cardiovascular disease and coronary heart disease. The properties of Ginkgo are mentioned here for example; improved blood flow, antioxidant, strengthens blood vessels, anti-inflammatory, relaxes the lungs, vasodilator and circulatory system tonic. Ginkgo biloba leaves extract also appears to have an anti-inflammatory impact that may make it useful in the future for situations like organ transplants and multiple sclerosis. However, due to the multi component of the herb, up to now the molecular mechanisms of action and signaling pathways leading to the therapeutic effects of GBLE remain, still, poorly understood.
  Akhtar Hussain Shar , Mohamed Shahen , Liujingjing , Shenfengxia and Yonghua Wang
  Cancer is an alarming condition whose occurrence has increased dramatically in the last few decades. This, in turn, has increased the medicinal cost and health care burdens of society. Unfortunately, a lack of effective and safe pharmacological therapy and strategies has been found to overcome this issue. Now-a-days nose cancer is an alarming health disorder that requires scientific attention to find an effective and safe pharmacological approach to overcome this serious issue. Currently, various treatments are used for this life threatening disease. Chinese traditional medicine like ginseng is one of the choices used as an effective and safe therapeutic tool for the treatment of cancer. Some previously published studies proved that ginseng not only kills the cancer cells but also inhibits the further multiplication of cancer cells with minimum side effects compared to the rest of treatment therapies. However, the exact mechanism of action behind ginseng’s ability to kill cancer cells has not been completely explored, there are still many research areas waiting to be studied, such as molecular pathways involved in the ginseng-derived flavonoids that attack cancer cells. The target of this review is to highlight the importance of the medicinal effects of ginseng and their flavonoids used in cancer therapy. Another objective of this paper is to attract the attention of the scientific community, to find out the mechanism of action behind ginseng herbal medicine in order to develop safe and non-toxic drugs for the cure of nose cancer.
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