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Articles by Manoj Bali
Total Records ( 2 ) for Manoj Bali
  Naresh Singh Gill , Ramandeep Kaur , Rashmi Arora and Manoj Bali
  Use of plants for health benefits is widespread in India. The present study was to investigate ethanolic seed extract of Caesalpinia crista for antioxidant activity by 1,1-diphenyl-2-picryl hydrazyl and hydrogen peroxide methods and anti inflammatory by Carrageenan induced paw edema and analgesic activity by writhing reflexes and by tail immersion method in mice. The extract showed potent antioxidant activity i.e., 73.9 and 77.7% at 300 μg mL-1 by 1,1-diphenyl-2-picryl hydrazyl and hydrogen peroxide method as compared to the standard (ascorbic acid). Further, the extract was evaluated for anti inflammatory activity and the extract showed maximum inhibition of 74.2% at 300 mg kg-1 by Carrageenan induced paw edema method as compared to standard (diclofenac). Furthermore, the extract was evaluated for analgesic activity the extract showed potent analgesic activity i.e., 71% at 300 μg mL-1 by writhing reflexes in mice and the tail withdrawal latency of mice was 5.30±0.05 sec at 300 μg mL-1 by tail immersion method. The present study concludes that Caesalpinia crista seeds have potent antioxidant, anti inflammatory and analgesic activity it can be used for therapeutic potential.
  Naresh Singh Gill and Manoj Bali
  The 9-beta-methyl-19-norlanosta-5-ene cucurbitane glycoside from Cucumis sativus seeds was evaluated for its antioxidant, antiulcer activity. Isolation was done by simple chromatographic technique. The evaluation of antioxidant activity by 1, 1-diphenyl-1-picrylhydrazyl and hydrogen peroxide method further more it was evaluated for antiulcer activity using pyloric ligation, water immersion and non steroidal anti-inflammatory drug (indomethacin) induced gastric ulcer model. The triterpenoid glycosides showed maximum antioxidant activity i.e., 73.21±3.11 and 71.63±2.51% by 1,1-diphenyl-1-picrylhydrazyl, hydrogen peroxide method at 300 μg mL-1, respectively as compared to ascorbic acid. Further, it was evaluated for anti ulcerogenic activity, the compound showed optimum percentage inhibition i.e., 56.6, 68.5 and 62.6% by pyloric ligation, water immersion stress and non steroidal anti-inflammatory drug (indomethacin) induced ulcer modal at 300 μg mL-1 against ranitidine in rats. Thus, it can be concluded that the isolated triterpenoid glycosides may be responsible for the antioxidant and antiulcer activity.
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