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Articles by M. Karandish
Total Records ( 6 ) for M. Karandish
  M.Mohammad- Shahi , H. Rafiei , M. Karandish , K. Omidian and F. Haidari
  It seems that soy isoflavones can improve obesity and reverse subsequent metabolic disorders. In this study we assessed the effect of restriction of calorie supplemented with genistein on diet-induced obese rats. Thirty male Wistar obese rats were divided randomly into 3 experimental groups (n = 10) as follows: group 1: low calorie diet supplemented with 50 mg kg-1 genistein, group 2: low calorie diet supplemented with dimethyl sulphoxide (as vehicle) and group 3: obese control rats with ad libitum access to standard food. The animals were carefully monitored and weighed daily. After 4 weeks, fasting blood samples were collected and analyzed for biochemical analysis. The results showed that the restriction of calorie intake caused to weight loss and subsequently led to a significant decrease in serum glucose (p<0.001), lipid profile (p<0.001) and hsCRP levels (p<0.001) but had no effect on resistin levels. Although, low calorie diet supplemented with genistein improved the lipid lowering effect of calorie restriction but this had no more effect on glucose, resistin and hsCRP levels. These results strongly suggest that low calorie diet supplemented with genistein is effective in weight management and has hypoglycemic, hypolipidemic and anti-inflammatory activities. However, it is not recommended before further investigations in animals and humans.
  S. Eslami , M. Karandish , S.M. Marandi and A. Zand-Moghaddam
  Physical activity changes hematological parameters in athletes which result in cessation of their exercises. There is limited data available about the effects of protein supplements on hematological parameters of resistance exercise. In this clinical trial, changes of hematological parameters were studied after one month resistance training and whey protein supplementation in 32 healthy young subjects (16 in supplement group and 16 in control group). Whey protein supplement (6.6 g day-1) and placebo (starch, in a same dose as the supplement) were consumed between meals. Every one exercised with 80% 1 RM, for 1 h a day, five days a week. Fasting blood specimens were taken before and after beginning of study and WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT and percent of WBCs were investigated separately. Student t-test and paired t-test were used for statistical analyses. WBC, RBC, HGB, HCT, PLT and MCHC levels in two groups significantly decreased (p<0.05), without any difference between two groups. MCV increased in the both study groups, but again there was no difference between them. MCH and lymphocytes% remained unchanged in both groups. In the supplement group, neutrophils % and other WBCs showed no noticeable changes, but in the placebo group, they were significantly increased and declined, respectively. However, no important difference was seen between two groups with respect to percentage of WBCs, separately. In conclusion, one month of whey protein supplementation with 6.6 g day-1 has no effect on hematological parameters changes after resistance exercise. Further studies with various dosages and longer periods of time are recommended.
  M. Karandish , S.T. Rahideh and A.Z. Moghaddam
  The aim of this double blind randomized controlled trial was to determine the effect of Vitamin C supplementation on oxidative stress following 30 min moderate intensity exercise. Forty-nine healthy young women randomly assigned into 500 mg day-1 vitamin C supplement (n = 25) or placebo (n = 24) groups for two weeks. Before supplementation and on the day after the intervention period, fasting blood samples were taken. Then all participants ran (1.4-1.7 m sec-1) for 30 min. Third blood samples were taken at the end of exercise. Plasma malondialdehyde (MDA) and vitamin C were measured using HPLC method. Plasma total glutathione was measured with ELISA method. No significant differences were observed in demographic and vitamin C intakes before intervention between groups. Plasma MDA levels decreased and plasma total glutathione increased significantly (p<0.05) in both groups. No significant differences were observed between groups after exercise. There were significant differences in plasma vitamin C concentrations after intervention and exercise between groups. In conclusion, vitamin C supplementation (500 mg day-1) for two weeks does not affect oxidative stress markers following moderate intensity exercise in healthy young women.
  S. Eslami , M. Karandish , S.M. Marandi and A. Zand-Moghaddam
  Physical activity increases protein catabolism and decreases plasma essential amino acids concentrations. Determining plasma amino acids concentrations is the method of choice for assessment of amino acids requirements of body organs. Few researches have been published about the effect of protein supplements, containing amino acids and other useful substances, on plasma essential amino acids concentrations in resistance athletes. This study was carried out to investigate the effect of whey protein supplementation on plasma essential amino acids concentrations, after resistance exercise in healthy athletes. In this clinical trial, changes of plasma essential amino acids concentrations were studied after 1 h exercise training and whey protein supplementation in 32 healthy volunteers (16 in each of supplement and placebo groups). Each day, whey protein supplement (20 g) and placebo (the same amount of starch) were consumed after training. Participants exercised with 80% 1 RM, basically on stationary circuit principal, for 1 h. Blood specimens were taken in fasting state, immediately after exercise and 1 h after supplement consumption. Essential amino acids concentrations were analyzed by HPLC. Statistical analysis were carried out using Student t-test and paired t-test. Treonine concentration increased significantly after exercise (p<0.05), but there was no difference between the two study groups. After supplementation, histidine concentration was unchanged in both groups. Treonine, arginine, methionine, valine, isoleucine and leucine concentrations increased significantly and phenylalanine concentration increased nonsignificantly in the supplement group. Treonine, methionine, valine, phenylalanine, isoleucine and leucine concentrations decreased significantly, but downward trend of arginine was not significant. Differences between the two groups were significant. The present study showed that 20 g day-1 of whey protein supplement is effective on plasma essential amino acids concentrations and compensated for their post exercise decrease.
  M.R. Vafa , M. Karandish , S.M. Mosavi , M. Alizadeh , M.H. Salehi and M. Maddah
  Riboflavin deficiency is one of the most common nutritional deficiencies, which has detrimental effects on physical growth of children. In the present study, the nutritional status of this vitamin in primary school children in Rafsanjan was investigated. In this cross-sectional study, the subjects were selected using multistage cluster random sampling and the general demographic data, including age and gender were collected by questionnaires. Urinary riboflavin level was measured as the indicator of riboflavin status. A moderate to severe riboflavin deficiency was found in half of the participants with a higher prevalence of severe deficiency in girls (p<0.005). Mean±SD of urinary riboflavin in male and female students were 392±381 and 421±546 μg g-1 creatinine, respectively. Based on findings of this cross-sectional study, riboflavin deficiency is a serious nutritional problem in primary school children, especially among female students.
  M. Karandish and M. Naghashpoor
  The aim of this cross-sectional study was to determine the calcium intake pattern among post menopausal women in Ahwaz, Iran. Fifty-three post menopausal women (age 57±9 year) were selected randomly. Calcium intake was estimated with a Food Frequency Questionnaire (FFQ) including fourteen items of the richest food sources of calcium. In order to evaluate calcium intake pattern, the food items divided into three categories, as dairy, grain and vegetable. Mean and standard deviation of total daily dietary calcium intake and from dairy, grain and vegetable groups were 984±354, 629±318, 200±133 and 167±151 mg, respectively. Mean and standard deviation of the daily total calcium contribution of dairy, grain and vegetable groups in calcium intake was 61±19, 22 ±16 and 17±14%, respectively. The results of this study suggested that the dietary calcium intake pattern in Ahwazian postmenopausal women is not suitable with regard to high servings of milk and dairy products; because of the effect of this food group (particularly, high fat items) on cardiovascular diseases.
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