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Articles by M. Amini
Total Records ( 5 ) for M. Amini
  D.D. Ganji , M. Amini and A. Kolahdooz
  Perturbation methods depend on a small parameter which is difficult to be found for real-life nonlinear problems. To overcome this shortcoming, two new but powerful analytical methods were introduced to solve nonlinear heat transfer problems in this Letter, one is He’s Variational Iteration Method (VIM) and the other is the Homotopy-Perturbation Method (HPM). Nonlinear hyperbolic equations were used as examples to illustrate the simple solution procedures. These methods were useful and practical for solving the nonlinear hyperbolic equation, which is associated with variable initial condition. Comparison of the results has been obtained by both methods with exact solutions reveals that both methods were tremendously effective.
  A. Kalbasi , M.A. Faramarzi , M.S. Hejazi , H. Jahandar , M. Amini and S.M. Jalali
  The potential of microalga Nostoc piscinale was evaluated in bioconversion of androst-4-en-3, 17-dione (I). Bio-reaction was performed in BG-11 liquid medium supplemented with 0.05% steroid substrate under continuous light photo-regime of 3000 lux at 25°C for 5 days. Three major metabolites were purified chromatographically and identified on the bases of their spectral data and physical constants as 17β-hydroxyandrost-4-en-3-one (II), 14α-hydroxyandrost-4-en-3,17-dione (III) and 14α,17β-dihydroxyandrost-4-en-3-one (IV). Bioconversion characteristics observed were 14α-hydroxylation and 17-keto reduction. Present results showed that the green biocatalyst is suitable for some specific alterations on androst-4-en-3,17-dione including 14α-hydroxylation.
  M. Amini , Kh. Abdi , M. Darabi and A. Shafiee
  A simple, sensitive isocratic method for detection and quantification of ofloxacin in plasma has been developed. The assay consisted of reversed HPLC with UV detection. Separation was achieved on a C18 column. The detection limit was 10 ng mL–1 in plasma. The validation data has been studied. This method provides sufficient sensitivity for pharmacokinetic studies and dose control in veterinary as well as in human medicine.
  H.R. Sadeghipour Roodsari , M. Amini , Z. Naghibi Harat , P. Daneshgar , M. Vosooghi and A. Shafiee
  In the present study, the activity of seven newly synthesized dihydropyridine analogues on the motility of sperm were determined and compared to nifedipine activity that was used as standard. Sperm motility reduced value for test compounds 6a-g shows a gradual increase proportional to the size elongation of alkyl ester groups. Consequently the size of alkyl is important in the activity of test compounds and finally increase in the lipophil size of hydrocarbon`s ester (R1) is inversely related to the activity of the synthetic compounds. As a result, the methyl ester of the test compounds with 50% of nifedipine activity (in two hours group) is the most active test compound.
  M. Amini and A. Tajik
  The aim of this study was to determine the efficacy of oral regimens in patients without active gastric bleeding and those of intravenous regimens in a group with active gastric bleeding. This study was performed as an interventional investigation in Tehran between April 2004 and March 2008. The patients who had active peptic ulcer were included and divided into two groups. One group included 26 subjects with active gastric bleeding and the other included 29 patients without active gastric bleeding. The intravenous treatment included metronidazole, ampicillin, ranitidine and orally administered bismuth for five days. The oral regimen included metronidazole, amoxicillin, ranitidine and bismuth sub-citrate for 14 days. In intravenous group 24 patients (92.3%) and in oral group 24 subjects (82.8%) had no drug adverse events. The successful treatment was seen in 61.5% (16/26) and 55.2% (16/29) in intravenous and oral methods, respectively. Finally, it may be concluded that both five-day intravenous therapeutic regimen in patients with active gastric bleeding and 14-day oral regimen in patients without active gastric bleeding would have good efficacy and low rate of drug adverse events.
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