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Articles by M. Zafer Ozel
Total Records ( 2 ) for M. Zafer Ozel
  Ijlal Ocak , Ali Celik , M. Zafer Ozel , Elif Korcan and Muhsin Konuk
  Endemic oregano’s, Origanum hypericifolium O. Schwartz and P.H. Davis, essential oil was extracted to exert its biological activity in vitro. Fifteen components in its extracts performed by hydro distillation. The major components in the fruit and flower volatiles of O. hypericifolium were p-cymene (34.33 g/100 g oil), carvacrol (21.76 g/100 g oil), thymol (19.54 g/100 g) and γ-terpinene (13.91 g/100 g oil). The antifungal activity of O. hypericifolium’s oil was evaluated against 14 fungi isolated from hazelnut and walnut. Nuts are capable of harboring toxigenic fungi and the threat of mycotoxin contamination on them exists. Essential oil of O. hypericifolium was found to be active both in contact and headspace assays in vitro producing hyphal growth inhibition. In the contact assay, P. frequentans was found to be the least sensitive species. The more sensitive species were P. castellonense, P. verrucosum. var. cyclopium, C. globosum, and A. kiliense. Their growth was completely (100%) inhibited at days 3 and 6. In the volatile assay, all the mycelial growth of all tested fungi was completely inhibited at day 3. The volatile activity was found to be highly efficient than that of contact activity assay. This could be because of the aromatic contents of Origanum, such as monoterpenes, carvacrol, thymol, and p-cymene.
  Ali Celik , E. Nur Herken , Idris Arslan , M. Zafer Ozel and Nazime Mercan
  The chemical compositions, total phenol content, antioxidant and antimicrobial activities with oxidant status of the essential oil from an endemic Turkish species, Origanum hypericifolium, were investigated. Steam distillation (SD) was used to isolate the essential oils, and the chemical analyses were performed by gas chromatography-mass spectrometry (GC-MS). The antimicrobial activity was tested by agar disc diffusion method against Morganella morganii (clinic isolate), Micrococcus flavus (clinic isolate), Micrococcus luteus NRLL B-4375, Proteus vulgaris RSKK 96026, Escherichia coli ATCC 11230, Escherichia coli ATCC 25922, Yersinia enterecolitica RSKK 1501, Staphylococcus aureus ATCC 25923, S. aureus ATCC 25933, S. aureus ATCC 12598, S. aureus (clinic isolate), MRSA 1 (clinic isolate), MRSA 2 (clinic isolate), MRSA 3 (clinic isolate) and MRSA 4 (clinic isolate). The major compounds found in volatiles of O. hypericifolium were p-cymene, carvacrol and γ-terpinene. Results showed that O. hypericifolium has the potential for being used in food and medicine because of its antioxidant and antibacterial activity.
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