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| Articles
by
M. Razi Jalali |
Total Records (
2 ) for
M. Razi Jalali |
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S.R. Fatemi Tabatabaei
,
A.A. Papahn
,
M. Razi Jalali
and
L. Rahimi
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Streptozotocin destroys the β-cells of pancreas
by generation of reactive oxygen species and vitamin E has documented
antioxidant properties. To evaluate the preventive effect of vitamin E
on induction of diabetes by streptozotocin and effect of oral vitamin
E consumption on carbohydrate and lipid metabolism, forty male Wistar
rats divided randomly to control, E1, E2 and E3
groups. The diet of E1, E2 and E3 groups
were supplemented with 1, 2 and 4 g kg-1 of vitamin E, respectively.
Four days later all rats were made diabetic by IP injection of 45 mg kg-1
streptozotocin and blood glucose was measured 72 h later to determine
the severity of blood glucose elevation. Glycosylated hemoglobin, triglyceride,
total cholesterol and HDL-c were measured and LDL-c and VlDL-c calculated
in plasma of 6 diabetic rats with glucose more than 200 mg dL-1
in each groups 21 days after streptozotocin injection. Vitamin E had no
effect on diabetes induction by streptozotocin, but elevation of glycosylated
Hb and reduction of LDL-c in group E3 were significant. Vitamin
E also increased HDL-c although it was not statistically significant.
We suggest that oral vitamin E consumption may have some beneficial effect
on the correction of lipid metabolism disorders of diabetes, although
it may worsen carbohydrate metabolism in mild diabetes. |
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R.A. Jafari
,
M. Razi Jalali
,
M. Ghorbanpoor
and
S.M.R. Marashian Saraei
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This study was designed to determine the effect of garlic
powder on humoral immune response of broilers against NDV (Newcastle Disease
Virus) vaccine. Two hundred and forty, two-day-old, Ross chicks were randomly
assigned into 4 groups of 60 birds each. Chicks in groups 1 and 2 were
given control mash diet during the experiment (6 week), but those in groups
3 and 4 were fed on control diet supplemented with 1 and 3% garlic powder,
respectively. All groups except number 1 were vaccinated by eye-drop with
B1 strain (Pestikal, Croatia) at 9 and 18 days of age. Ten blood samples
were taken from each group on days 0, 14, 24 and 34 after first vaccination.
The serum antibody level against NDV was measured by both HI and ELISA
tests. The EDTA-mixed blood samples were examined for total and differential
leukocyte count. The results showed that antibody titers in vaccinated
chicks were significantly more than in non-vaccinated chicks (p<0.05),
but not influenced by the diet (p>0.05). A significant increase of
total leukocyte and percentage of lymphocytes was observed in vaccinated
chicks 14 days after vaccination, but there were no difference (p>0.05)
among vaccinated groups. It is concluded that inclusion of garlic powder
to the diet of broilers don`t have any beneficial effect on humoral immune
response to live NDV vaccine. |
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