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Articles by M. Ekramul Haque
Total Records ( 2 ) for M. Ekramul Haque
  M. Motiur Rahman , Mir Imam Ibne Wahed , M. Helal U. Biswas , Md. GolamSadik and M. Ekramul Haque
  The research work was conducted to investigated the in vitro antibacterial activity of the compound isolated from Trapa bispinosa. Antibacterial activity of the compounds was observed against fifteen pathogenic organisms (both Gram positive and Gram negative Bacteria) by disc diffusion method. Compound MTC-4 isolated from chloroform extract showed significant in vitro antibacterial activity against almost all of the test organisms but maximum activity showed against Bacillus subtilis and shigella  dysenteriae and produced zone of inhibition in between 12 to 15mm. While the compound MTE-1 showed moderate activity (08 to 12mm) against most of the test organisms. The other two compounds MTC-3 and MTC-5 were found comparatively less active. The MIC values of the compounds were also determined against two test organisms Bacillus subtilis and Shigella dysenteriae. The values were found to be between 8 to 128μg ml‾1. Thus MTC-4 possesses strong antibacterial activity and suggested its therapeutic use as an antimicrobial agent.
  M. Rowshanul Habib , Farjana Nikkon , Matiar Rahman , M. Ekramul Haque and M. Rezaul Karim
  Aim of this study is to identify and characterize the bioactive principles from the root bark of Calotropis gigantea. It has wide folk medicinal use. For isolation of the compounds, the dried root bark’s powder of calotropis gigantea were subjected to hot extraction and then the crude methanol (MeOH) extract was fractionated with petroleum ether, chloroform and ethyl acetate. Two compounds were isolated and purified from petroleum ether fraction of crude methanol extract and the structures were determined as stigmasterol and β-sitosterol by analysis of physical, chemical and spectral characteristics (1D NMR and mass spectrometry).
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