Overexpression of Neprilysin Reduces Alzheimer Amyloid-β42 (Aβ42)-induced Neuron Loss and Intraneuronal Aβ42 Deposits but Causes a Reduction in cAMP-responsive Element-binding Protein-mediated Transcription, Age-dependent Axon Pathology, and Premature Death in Drosophila

Kanae Iijima-Ando, Stephen A. Hearn, Linda Granger, Christopher Shenton, Anthony Gatt, Hsueh-Cheng Chiang, Inessa Hakker, Yi Zhong and Koichi Iijima

The Journal of Biological Chemistry 283 ( 27 ): 19066 - 19076 , 2008