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Articles by Jung Eun Kim
Total Records ( 2 ) for Jung Eun Kim
  Jung Eun Kim , Sang Suk Kim , Chang-Gu Hyun and Nam Ho Lee
  Chemical investigation to identify the antioxidative constituents from the stems of a tree Cleyera japonica Thunb. resulted in the isolation of seven compounds: catechin (1), catechin 3-O-α-L-rhamnopyranoside (2), epicatechin (3), taxifolin (4), taxifolin 3-O-α-L-arabinopyranoside (5), taxifolin 3-O-α-L-rhamnopyranoside (6) and proanthocyanidin A-1 (7). These isolates were studied for their scavenging activities against DPPH radical, hydroxyl radical and superoxide anion radicals using spectrophotometry and/or electron spin resonance. All isolates 1-7 exhibited more potent DPPH radical inhibition activities than the positive control, ascorbic acid. In the hydroxyl radical scavenging test, compound 7 (SC50 301.6 μM) showed potent activity higher than ascorbic acid (SC50 859.7 μM). All of the compounds 1-7 exhibited comparable activities to ascorbic acid for superoxide anion radical scavenging. These results demonstrated that C. japonica stem extracts could be potentially used as antioxidative agents in food or cosmetic applications.
  Jennifer L. Jones , Maria Luz Fernandez , Mark S. McIntosh , Wadie Najm , Mariana C. Calle , Colleen Kalynych , Clare Vukich , Jacqueline Barona , Daniela Ackermann , Jung Eun Kim , Vivek Kumar , Michelle Lott , Jeff S. Volek and Robert H. Lerman
 

Background

The high prevalence of metabolic syndrome (MetS) has highlighted the need for effective dietary interventions to combat this growing problem.

Objective

To assess the impact of a Mediterranean-style low-glycemic-load diet (control arm, n = 44) or the same diet plus a medical food containing phytosterols, soy protein, and extracts from hops and acacia (intervention arm, n = 45) on cardiometabolic risk variables in women with MetS.

Methods

In this 12-week, 2-arm randomized trial, baseline, week 8 and 12, fasting blood samples were drawn to measure plasma lipids, apolipoproteins, and homocysteine. Dietary records were also collected and analyzed.

Results

There were decreases in fat and sugar intake (P < .001 for both) and increases in docosahexaenoic acid and eicosapentaenoic acid intake (P < .001 for both) over time, consistent with the prescribed diet. Regarding MetS variables, there were decreases in waist circumference, systolic and diastolic blood pressure, and plasma triglycerides in all subjects (P < .001 for all) with no differences between arms. Plasma low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, apolipoprotein (apo) B, and apo B/apo A1 were reduced over time but to a greater extent in the intervention arm (P < .05 for all), indicating the medical food had a greater effect in altering lipoprotein metabolism. Further, medical food intake was associated with reduced plasma homocysteine (P < .01) compared to the control arm.

Conclusion

A Mediterranean-style low-glycemic-load diet effectively reduces the variables of MetS. Addition of the medical food results in a less atherogenic lipoprotein profile and lower plasma homocysteine.

 
 
 
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