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Articles by Ismail Kucukkurt
Total Records ( 1 ) for Ismail Kucukkurt
  Gulcan Avci , Ismail Kucukkurt , Esra Kupeli Akkol and Erdem Yesilada
  Escins, a triterpene glycoside mixture obtained from the ethanol extract of Aesculus hippocastanum L. (Hippocastanaceae) seed, was evaluated for its in vivo effects on the plasma levels of some hormones (leptin, insulin, FT3, FT4) and biochemical parameters (glucose, triglyceride, total cholesterol, HDL - C, LDL - C concentrations) in mice fed with a high fat diet for 5 weeks. A high fat diet induced a remarkable increment in the plasma leptin (p <0.01), total cholesterol (p <0.01) and LDL - C (p <0.001) concentrations compared to control group animals. Combined administration of a high -fat diet with escins decreased leptin (31.6%) (p<0.05) and FT4 (36.0%) (p<0.05) levels, increased HDL - C concentration (17.0%), while remained ineffective on LDL - C concentration in mice. Results have shown that escins may have beneficial effects in the understanding of obesity.
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