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Articles by H.R. Arab
Total Records ( 3 ) for H.R. Arab
  N. Sargolzaei , H.R. Arab , A. Moeintaghavi , H. Ghanbari , A. Rigi and M. Hosseini Hoshyar
  The major aim of periodontal treatment is reconstruction of broken tissues and maintenance of periodontal health. Different chemotherapeutic agents are used to change the host response to bacterial irritants along with nonsurgical and surgical periodontal therapies. Doxycycline is one of these agents used widely due to its anticollagenolytic and antibacterial properties. The aim of this study was to evaluate the effect of long-term usage of low dose doxycycline after periodontal surgery in the treatment of chronic periodontitis. In this study, 30 patients with chronic periodontitis were selected. After initial therapy and periodontal surgery, all patients were recalled and Probing Depth (PD), Attachment Level (AL) and Bleeding on Probing (BOP) indices were measured. Then they randomly allocated to test and control groups. In the test group (15 patients) all patients received 90 capsules (20 mg doxycycline) to use one cap per day for the following 3 month. The controls received the same shape and color placebo capsules. All the patients were recalled after one and 3 month and the above mentioned parameters were recorded again. The results showed significant reduction in PD and AL in the test group. Bop did not change significantly in both groups. PD and CAL increased in the control group but these increases were significant only for PD. The results of this study showed that the use of low dose doxycycline along with supportive periodontal treatment and oral hygiene during maintenance period can improve the clinical parameters.
  M. Radvar and H.R. Arab
  The aim of present study was to evaluate the frequency of 3 members of herpes virus family in the subgingival plaque samples from periodontal pockets and healthy sites of an aggressive periodontitis population. Fifteen subjects with aggressive periodontitis took part in this study. Subgingival plaque samples were harvested from their 3 deepest pockets and 3 healthy sites and subjected to a nested Polymerase Chain Reaction (PCR) technique to detect Human Cyto–megallo Virus (HCMV), Epstein Barr virus 1 (EBV–1) and Herpes Simplex Virus 1 (HSV–1). Seven individuals revealed HCMV in their diseased sites while only 2 of these individuals revealed HCMV at their healthy sites too. Three individuals showed EBV–1 only at their diseased sites, while the remainig diseased sites and all healthy sites were negative for this virus. Finally, HSV–1 was found only at one of the diseased samples, but none of the healthy samples. Members of the Herpesvirus family might be recovered at periodontal sites. The prevalence of these viruses seems to be greater at diseased sites than healthy sites. Herpesviruses might be involved in the pathogenesis of periodontal disease.
  N. Sargolzai , A. Moeintaghavi , M. Sanatkhani , H.R. Arab and H. Bazyar
  The aim of this study was to evaluate the relationship between periodontal diseases and C reactive protein level. Fifteen patients (7 male, 8 female, mean age 34±11.6) with chronic periodontitis and 15 ages and sex matched (7 male, 8 female and mean age 29±10.4) periodontally healthy subjects recruited from the patients referred to the department of periodontics, Mashhad Faculty of Dentistry. In all the patients and controls Body Mass Index (BMI) was under 30 kg m-2. Periodontal probing depth of Ramfjord teeth were recorded for both groups. Peripheral blood samples were collected and sent to the laboratory to determine the amount of CRP using a semi-quantititative method. The amount of CRP in the test group was 4.1 mg L-1. In the control group it was 0.18 mg L-1. CRP in the test group was significantly higher than the control group (p = 0.008). There was no significant correlation between the mean pocket depth and the CRP levels. Sex and age did not affect the amount of plasma CRP. Periodontal diseases can increase the amount of plasma CRP. This might be due to the infective nature of periodontal diseases.
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