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Articles by Glory Otuchristian
Total Records ( 3 ) for Glory Otuchristian
  N.A. Obasi , E.I. Akubugwo , O.C. Ugbogu and Glory Otuchristian
  Physico-chemical parameters (pH, EC, %moisture, CEC, TOC, TOM, total nitrogen, %PO43¯, SO42¯) and the chemical fractionation, mobility and bioavailability of heavy metals (Cd, Cu, Mn, Pb, Zn, Fe, Ni and Cr) in refuse waste soils of some dumpsites along Enugu-port Harcourt Expressways, South-East, Nigeria were investigated and compared with control soils from the same terrain using standard analytical methods. Results showed significant (p>0.05) higher changes in the soil physico-chemical properties relative to the controls, thus implicating the waste soils to be more fertile. Also, mean of total extractable metals in the samples analyzed for Cd, Cu, Mn, Pb, Zn, Fe, Ni and Cr ranged from 23.41-107.18, 10.58-238.50, 141.21-442.03, 35.11-635.31, 186.38-505.57, 76.46-371.73, 13.00-221.97 and 13.55-26.77 mg kg-1 dry weight, respectively. Cd followed by Fe and then Pb were mostly found to be in the mobile phase of the samples indicating that the metals were potentially more bio-available to the environment than the other metals studied. Overall, the order of mobility and bioavailability of the metals is Cd>Fe>Pb>Mn>Zn>Cr>Ni>Cu. The implications of these results towards the understanding of the underlying causes of plants species diversity changes and growth, bioaccumulation and bio-toxicity of some edible plants on dumpsites were discussed.
  Nwogo Ajuka Obasi , Kalu Mong Kalu , Uchechukwu Okorie and Glory Otuchristian
  The hypoglycemic effects of aqueous and methanolic leaf extract of Vitex doniana were evaluated in normal and alloxan-induced diabetic rats using standard analytical protocols. The potency of the leaf extract was compared with that of oral anti-diabetic agent (Glibenclamide). A total of 35 albino rats divided into seven groups of five rats each comprising one normal untreated group as animal control, one diabetic untreated group as diabetic control, one normal treated with 750 mg kg-1 b.wt. as reference group, three diabetic groups treated with 250, 500 and 750 mg kg-1 body weight respectively and one diabetic group treated with 5 mg kg-1 Glibenclamide as standard. The result of acute toxicity test obtained indicated lethal dose (LD50) of greater than 5000 mg kg-1 extract. Results indicated that administered doses of 250, 500 and 750 mg kg-1 body weight of the leaf extract showed significant (p<0.05) reduction of blood glucose level, renal function markers (serum creatinine, urea and uric acid) and serum electrolytes (Potassium and sodium ions) in a dose dependent manner in reference and diabetic groups when compared to normal and diabetic control groups, respectively. The results also indicated that administration of the extracts caused a significant (p<0.05) increased in the serum total proteins and albumin levels and a significant (p<0.05) decrease in the total bilirubin levels in the diabetic rats. These results imply that the leaf extract is relatively safe and could be used in the management of diabetes mellitus and associated complications.
  Kalu Mong Kalu , Nwogo Ajuka Obasi , Florence Onyemachi Nduka and Glory Otuchristian
  Malaria is an infectious disease which is as old as man and as such demands a thorough put investigation for effective prevention. In this study, a comparative study of the prevalence of malaria in Aba and Umuahia urban settings of Abia state, Nigeria were investigated in order to proffer possible preventive/control measures. A total of 500 individuals (250 in each urban setting) were examined for malaria parasites in blood specimens using standard methods. The results showed that a total number 402 (80.40%) were positive for malaria parasitaemia. In Aba, 216 (86.40%) individuals were positive while in Umuahia, 186 (74.40%) individuals were positive for malaria parasitaemia and the difference in the prevalence between these urban areas were statistically significant. Individuals of age group 21-30 years had the highest rate of infection (92.31%) in Aba while in Umuahia highest infection rate of 90.00% was observed in the age group 11-20 years. Traders were mostly infected in both urban areas with 94.34% in Aba and 93.75% in Umuahia, however, the difference was not statistically significant (p>0.05). Females in both urban areas were more infected than males with (91.20%) in Aba and 80.80% in Umuahia, the difference being statistically significant (p<0.05). Plasmodium falciparum, Plasmodium vivax and Plasmodium malariae occurred in both urban areas with Plasmodium falciparum predominating Aba and Umuahia urban were observed to be endemic for malaria.
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