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Articles by G. Phani Kumar
Total Records ( 3 ) for G. Phani Kumar
  T. Anand , G. Phani Kumar , N. Ilaiyaraja , Farhath Khanum and A.S. Bawa
  The present study was undertaken to elucidate the mechanism responsible for ameliorating effect of asiaticoside rich Centella asiatica leaf extract (CAE) on fatigue. CAE at 10 mg kg-1 b.wt. was administered orally to rats for 2 weeks and subjected to weight-loaded forced swim test (WFST) every alternative day for a period of three weeks to evaluate physical fatigue. CAE administrated rats prolonged the swimming time for exhaustion almost two fold compared to the control. Moreover, WFST also reduced the levels of glycogen content in muscle and liver tissues and activities of superoxide dismutase and catalase in liver and brain tissues. These effects were reverted back with the administration of CAE and therefore it is concluded that C. asiatica extract ameliorates the various impairments associated with physical fatigue in enhancing the physical endurance capacity.
  Raj Kumar , G. Phani Kumar , OP Chaurasia and Shashi Bala Singh
  Hippophae rhamnoides L. (Elaeagnaceae) also known as seabuckthorn, is a thorny, deciduous, temperate bush plant native to European and Asian countries. In India, it is widely distributed at high altitude, cold arid condition of Ladakh (Leh and Kargil), Himachal Pradesh, Sikkim and Arunachal Pradesh. H. rhamnoides has been used for the treatment of several diseases in traditional medicine in various countries throughout world. In Ladakh, the Sowa Rigpa system (Amchi System of medicine) has been using the plant parts in different herbal formulations. However, more scientific data is needed to support the various health claims. The various in vivo study of seabuckthorn oil reported to have anti-inflammatory, antioxidant, antimicrobial, anti-ulcer properties and hepatoprotective. Seabuckthorn oil is a unique source of high valued oils emphasizing its potential as a dietary and medicinal supplement and has become noted for its generally high levels of nutritionally and medicinally important components. The major unsaturated fatty acids were linolenic acid (omega-3) (20-23%), linoleic acid (omega-6) (40-43%), oleic acid (omega-9) (19-22%) and palmitoleic acid (1-3%) while the major saturated fatty acid contents were palmitic acid (7-9%), stearic acid (3-4%) in seed oil. Seabuckthorn pulp oil contains approximately 65% combined of the monounsaturated fatty acid and the saturated fatty acid. Both the seed and pulp oils are rich in Vitamin-E and β-Sitosterol. In addition, the pulp oil contains especially high levels of carotenoids. This ancient plant with its powerful and healing synergies has much to contribute to the livelihoods of high mountain people by utilizing this kind of hidden treasure of the Himalayas. In this review discusses on traditional use, phytochemistry and pharmacological data of the seabuckthorn oil.
  G. Phani Kumar , Raj Kumar and O.P. Chaurasia
  The study reveals that Ladakh is rich in medicinal flora and endemic diversity. The traditional knowledge on native plant species is highlights Amchi system of medicine and their traditional health-care system. The excessive extraction of medicinal plant resources for use in the pharmaceutical industry has resulted in ruthless destruction of natural populations of medicinal plants. Present study attempts to assess the current status of knowledge of medicinal plant resources and conservation status in Ladakh. An approach for prioritizing strategies for action is proposed which is a three step process, viz., technology development, technology dissemination, technology assessment and refinement. It also focuses on approach for prioritizing strategies for action is proposed.
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