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Articles by Chiung-Chi Peng
Total Records ( 2 ) for Chiung-Chi Peng
  Chao-Ming Chuang , Hui-Er Wang , Chiung-Chi Peng , Kuan Chou Chen and Robert Y. Peng
  Context: In utilization of Alpinia zerumbet (Pers.) Burtt and Smith (Zingiberaceae) (AZ), usually the angiocarps are discarded without further use. Objective: We speculate whether the angiocarps could show hypolipidemic effect. Methods and methods: Several diets were prepared: Alpinia seed powder (ASP); Alpinia seed powder/husk (ASH): 40/60; and Alpinia seed essential oil (ASO): 0.01−0.10%. Sprague-Dawley rats divided into 11 groups were fed these diets for 8 weeks and tested for the hypolipidemic bioactivity. Results: The fecal neutral cholesterol excretion was increased, and the serum total triglyceride (TG) was significantly reduced from 153.7 mg/dL in the high-fat group (H) to 114.3−119.8 mg/dL by ASO; to 116.3−147.9 mg/dL by ASP; and to 116.2−145.3 mg/dL by ASH. Activity of superoxide dismutase (SOD) and glutathione peroxidase (GPX) were almost unaffected. The high-density lipoprotein (HDL) levels were mostly raised by ASO to 180.3−200.8 mg/dL. The low-density lipoprotein (LDL) levels were mostly reduced to 66.8−82.6 mg/dL by ASH. The level of arachidonic acid was mostly raised to 0.50−0.60% by ASO, compared with 0.37% of group H. More importantly, the significant reduction in hepatic TG and total cholesterol (TC) implicated a crucial liver protective effect. Discussion and conclusion: ASP and ASH consisted of high crude-fiber content, while ASO consisted of seed essential oil. Both the seed essential oil and the whole powder of AZ previously had been reported to possess potent hypolipidemic bioactivity. Conclusively, the hypolipidemic effect can be attributed to the combined effect of the essential oil and the crude fiber.
  Chia-Hung Liu , Chiung-Chi Peng , Chiung-Huei Peng , Chiu-Lan Hsieh , Kuan-Chou Chen and Robert Y. Peng
  Diabetes Mellitus (DM) related Advanced Glycation End products (AGEs) are considered to induce functional impairment of cavernosal smooth muscle relaxation and cause Erectile Dysfunction (ED). We used rats to examine the in vitro effects of Psidium guajava L. (Myrtaceae) budding leaf extract (PE) on pharmacological relaxation of corpus cavernosum smooth muscle strips obtained from diabetic rats. After 8 weeks, the mean glycosylated haemoglobin (HbA1c), serum cholesterol and triglyceride concentrations were significantly higher in the non-PE diabetic than in the age-matched control animals. Interestingly, in diabetic animals fed PE, serum cholesterol and triglyceride levels were significantly lower than in their peers given a standard diet. The administration of PE to diabetic animals for 8 weeks reversed the expected impaired relaxation response and nitric oxide production in cavernosal smooth muscle exposed to acetylcholine or electrical field stimulation. The administration of PE to rats with 8 weeks of uncontrolled diabetes reverses DM-induced harmful effects on vascular smooth muscle.
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