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Articles by Azad Reza Mansourian
Total Records ( 5 ) for Azad Reza Mansourian
  Ezzat Ollah Ghaemi , Kiomarse Ghazesaeed , Farhdokht Fatemi Nasab , Zahra Hashemzade , Shide Vatani , Maryam Mohamedi and Azad Reza Mansourian
  Mycobacterium marinum is the etiologic agent of fish tank granuloma in human. Determination of the fish tank granuloma in Fishermen and Mycobacterium marinum infection in Caviar fishes in Ashorade, in south east Caspian Sea were our objectives. Any suspected lesions in 387 subjects of Fishermen and 113 autopsy samples from gills of fish of Caviar were obtained and culture in Lowenstein Jensen media. The mycobacterial species were determined by conventional biochemical tests. No fish tank granuloma was proved in human, but 11 (9.73%) strains of Mycobacteria were isolated from Caviar fishes, that only 2 strains (1.76%) belong to M. marinum.
  Hamid Reza Joshaghani , Azad Reza Mansourian , Khodaberdi Kalavi and Saideh Salimi
  The purpose of this study was to evaluate the effect of pesticides on blood indices of subjects which are exposed to organophosphate toxins. This research was a cohort study which was carried out during 2005 on the employee of a pesticide factory in Golestan province (North of Iran). In this study the sampling from 63 subjects was carried out for two sessions in days 1 and 90. CBC and hematologic indices performed by cell counter instrument. The mean of MCV in phase 1 was 82.8±7.1 fl and in second phase the MCV was 80.3±6.7 fl. This drop in MCV statistically was meaningful (paired t-test, mean = 2.5, 95% CI=2.0-2.9, p<0.001). Erythrocyte number, hemoglobin, HCT and MCHC increase in second phase compared to first phase statistically was meaningful. There was not any significant relation between the place of work and variation of red blood cell indices. In regard to the changes in hematologic indices in workers of pesticide factory in a three months period, it seems logical to set up a program to have a routine check on the hematologic indices in working personal engaging in such occupations.
  Vahid Khori , Mohsen Nayebpour and Azad Reza Mansourian
  In the present study we used isolated perfused AV-node of rabbit as an experimental model to determine the effect of various concentrations of extract of C. sativus (A = 9x10-2, B = 19x10-2, C = 28x10-2, D = 37x10-2 mg L-1) on electrophysiological properties of isolated heart. Selective stimulation protocols were used to independently quantify AV nodal recovery, facilitation and fatigue in 12 rabbits. Our results showed concentration dependent depressant effects of aqueous extract of C. sativus on Wenchebach Cycle Length (WBCL), AV Conduction Time (AVCT), Functional Refractory Periods (FRP). C. sativus (28x10-2 mg L-1) prolonged AVCT from 44.4±5 (control) to 52.2±4 m sec, Rate-dependent properties such as Facilitation and fatigue significantly increased by 19x10-2 mg L-1 of C. sativus. In control group magnitude of fatigue was 6.7±0.6 and increased by Saffron to 20±11.5 (p< 0.05). The effect of extract was prominent on fast pathway. The above results indicated differential effects of C. sativus on slow and fast pathways which has a dominant role on the fast pathway. This research for the first time has explained the role of saffron on the protective mechanism of artrioventricular node against supraventricular arrhythmia. These results showed the non-specific effect of saffron on the transitional cells of fast nodal pathway which was manifested as a rate-independent increase of basic and functional (facilitation and fatigue) parameters of artrioventricular node.
  Ezzat Ollah Ghaemi Ghaemi , Didar Khorshidi , Abdolvahab Moradi , Akhter Seifi , Masomeh Mazendrani , Masod Bazouri and Azad Reza Mansourian
  Daily increasing of Staphylococcus aureus resistance to various antibiotics in particular penicillin and Methecilin has led the scientist to look fore new medicines in this area. In an in vitro laboratory studies, it has been demonstrated that ethanolic extract of Lemon verbena can prevent the growth of Staphylococcus aureus. In this study the efficacy of ethanolic extract of Lemon verbena against Staphylococcus aureus skin infection were assessed in an in vivo, in animal model. 200 λ of Staphylococcus aureus suspension, were inoculated intradermally on the shoulder of 63 laboratory 20-30 g mice. the mice were divided in to 4 groups, 2 control groups: Negative (without treatment) and positive(treated with Mupirucin) and 2 test groups that treated for 7 days by ointment prepared from ethanolic extract of Lemon verbena (group3), or injection of Lemon verbena solution (group 4). The status of wounds, the rate of recovery was studied and the presence of local pus after dissection of mice on day 8 recorded and compared with each other. The wound appearance in the second day, on the injection site of S. aureus, in Group 1, 4, 3 and 2 were 84.2, 66.7, 46.2 and 23.1%, respectively. In the final day, the lesion still was remained in 78.9, 23.1, 92.3 and 77.7% in groups 1 -4, respectively. The necrotic and wide wounds were more observed in groups 1 and 3 vs two other groups. The results from this investigation indicate that the ointment prepared from ethanolic extract of Lemon verbena is a proper medication to prevent the skin infection by Staphylococcus aureus in early phase.
  Ezzat Ollah Ghaemi , Azad Reza Mansourian , Ali Reza Ahmadi , Mohsen Saeidi , Abdolvahab Moradi and Naser Behnampour
  Institutionalization of Mental Retarded (MR) children increase the risk of infections. In this study, we aimed at investigation the frequency of Streptococcus pyogenes, Brucella species and Salmonella species, infection among children with mental retardation living in Golestan Province in North of Iran. The study included 304 MR and 302 Healthy subjects who comprise the control group. ASO, Wright, 2ME, Widal and CRP were investigated in all serum samples, using Agglutination method. ASO positive test were 24.9 and 18.7% and the frequency of positive Wright test were determined 3.6 and 0.7% in MR and healthy children, respectively. Neither of the children in 2 groups has positive Widal test. The CRP positive test in MR children which was 4.9% were more than healthy children. The high frequency of streptococcal infection suggests that mental retarded children in our region need particular attention about the development of post-streptococcal infectionsequel.
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