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Articles by Ahmed Alhaidary
Total Records ( 6 ) for Ahmed Alhaidary
  Ahmed Alhaidary , H. E. Mohamed and A. C. Beynen
  Problem statement: There is evidence that the type of fiber influences the development of nephrocalcinosis in rats, but the effect of pectin was unknown. Approach: The effects of dietary pectin and cellulose on kidney calcification were studied in female rats. The diets used contained either 0.4-0.6% phosphorus and either cellulose (10%, w/w) or pectin. The purified diets used were balanced for residual calcium, magnesium and phosphorus in the fiber preparations. Results: Increasing the phosphorus concentration of the diet from 0.4-0.6% caused massive nephrocalcinosis in rats fed the cellulose diets. Pectin (10%, w/w) versus cellulose in diets containing 0.4% phosphorus significantly increased calcium and phosphorus concentrations in kidney. When compared with cellulose, pectin did not influence the apparent absorption of calcium, phosphorus and magnesium. Urinary concentrations of calcium and magnesium were not affected by pectin feeding, but those of phosphorus were increased. When pectin was given with the diet containing 0.6% phosphorus, its nephrocalcinogenic action as compared with cellulose was not observed. Conclusion: Pectin instead of cellulose in diets containing 0.4% phosphorus induced nephrocalcinosis in female rats. The effect of pectin may be explained by an increase in urinary phosphorus concentration. The lack of nephrocalcinogenic action of pectin in a diet with 0.6% phosphorus indicates that the nephrocalcinosis-inducing effect of high phosphorus intake had overruled any effect of fiber type.
  Nabiela M. El Bagir , Imtitha T. O. Farah , Safia M. B. Elhag , Ahmed Alhaidary , Hasab E. Mohamed and Anton C. Beynen
  Problem statement: The consumption of black cumin (Nigella sativa) seed has immunomodulatory and anti-bacterial activity, but in rabbits this had not yet been tested. Approach: In the present studies, rabbits were fed diets without or with black cumin seed and antibody production, phagocytotic activity, hypersensitivity and resistance against Pasteurellosis were assessed. Results: Feeding black cumin seed significantly increased serum concentrations of antibodies in response to intramusculary injected serum bovine albumin. Blood derived from rabbits fed the diets containing either 15 or 20% black cumin seed significantly reduced the growth of Staphylococcus aureus on sheep-blood agar plates. Skin thickness as index of hypersensitivity towards tuberculin was significantly reduced at 48 h after intradermal injection of the agent. Ingestion of black cumin seed significantly extended survival time after intraperitoneal administration of Pasteurella multocida. Conclusion: The feeding of black cumin seed to rabbits stimulated their immune system, but did not enhance inflammation.
  Nabiela M. El Bagir , Imtithal T.O. Farah , Ahmed Alhaidary , Hasab E. Mohamed and Anton C. Beynen
  Ingestion of black cumin seeds has wide variety of biological effects, implying that different processes in the body are influenced simultaneously. To assess to what extent clinical laboratory serum values are affected, rabbits were fed diets containing different levels of whole black cumin seed and serum was collected at various intervals. The base diet consisted of 60% lucerne and 40% sorghum. To formulate the experimental diets either 10, 15 or 20% of the base diet was replaced by black cumin seed. Body-weight gain was increased by the diets with 10 or 15% black cumin but not by the diet with 20%. Dietary black cumin seed raised serum concentrations of total protein, albumin and globulin but the diet with 20% produced lower values than did the 10 and 15% inclusion levels. Black cumin feeding increased serum urea and creatinine and lowered uric acid concentrations. Serum glucose, total lipid and cholesterol concentrations were lowered by consumption of black cumin. Black cumin seed in the diet did not affect the serum activities of alkaline phosphatase and glutamate pyruvate transaminase. Serum sodium and potassium were not influenced by black cumin but serum calcium and phosphate concentrations were increased. The major finding in this study with rabbits is that the highest dietary level of 20% versus either 10 or 15% black cumin seed lowered serum protein concentrations and diminished weight gain.
  Bakheit A. Yagoub , Ahmed E. Amin , Nabiela M. El Bagir , Ahmed Alhaidary , Hasab E. Mohamed and Anton C. Beynen
  Laying hens were fed diets containing either black cumin seed or white wormwood leaves or the combination of the two additives and the effects on egg production and egg quality characteristics were determined. Final body weights were significantly increased in the birds fed the diet with 1% black cumin seed and in those fed the diet with 0.5% of both black cumin seed and white wormwood leaves. Feed intake was numerically lower after the feeding of the diets with 1% white wormwood leaves. Egg production was not significantly influenced by dietary treatment but group-mean egg production was lowered in the hens fed the diet with 1% black cumin seed. Feed conversion efficiency was significantly decreased by the diet containing 1% white wormwood leaves and by the diet with the combination of 1% of black cumin seed and 1% white wormwood leaves. The diet containing 0.5% black cumin seed plus 0.5% white wormwood leaves also significantly decreased feed conversion. Egg weight, shape index, albumen height, Haugh unit, shell thickness and yolk color were not significantly affected by the dietary treatments. The major finding of this study may be that dietary white wormwood improved feed efficiency in laying hens whereas black cumin seed did not.
  Nabiela M. El Bagir , Rania T.H. El Amin , Ahmed Alhaidary , Hasab E. Mohamed and Anton C. Beynen
  In this study with rats, the influence of a dietary black cumin seed on both serum proteins and blood cell counts was determined. Rats were fed a diet either without or with 15% black cumin seed for 9 weeks. At the end of the experiment, body weights were similar for the two groups of rats. The diet containing black cumin seed slightly but significantly, lowered the concentration of plasma total proteinsbut did not affect the concentrations of albumin, globulins and hemoglobin. The numbers of white and red blood cells were not affected by black cumin seed in the diet and so was the the composition of white blood cells in terms of neutrophils, lymphocytes and monocytes. After comparing the results of this study with those of studies found in the literature data, it is concluded that black cumin seed has clear effects on serum proteins and blood cells only in rats that are exposed to toxic agents.
  Lymia H.A. Majeed , Khadiga A. Abdelati , Nabiela M. El Bagir , Ahmed Alhaidary , Hasab E. Mohamed and Anton C. Beynen
  An overview of the literature indicates that lower rather than higher dietary concentrations of black cumin seed may have a positive influence on feed efficiency in broiler chickens. In this study, 4 day old broiler chickens were fed either a diet without or with black cumin seed at inclusion levels of 0.25, 0.50 or 0.75% for a period of 7 weeks. Body weight gain during the 1st, 4th and 7th week of the experiment was significantly decreased by each level of dietary black cumin. The diets containing black cumin seed did not significantly influence weight gain and feed efficiency as measured for the entire experimental period. However, the diets with either 0.25, 0.50 or 0.75% black cumin lowered group-mean weight gain by 4.7, 3.3 and 6.5%, respectively and raised the group-mean feed conversion ratio (g feed/g weight gain) by 3.7, 4.8 and 7.0%. The final weights of breast, thigh and drumstick were not affected by the composition of the diet. It is concluded that dietary black cumin seed may deteriorate feed efficiency in broiler chickens in a dose-dependent relationship. It is unclear why the present observation is opposite to the outcome of various earlier studies of other investigators.
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