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Articles by Zakir Shahida
Total Records ( 2 ) for Zakir Shahida
  Iqbal Zafar , Shaheen Mussarat , Hussain Farrakh , Baig Sheraz , Ismail Mohammad , Zakir Shahida and Ahmad Bashir
  The research work was conducted to investigate the antifungal activity of hexane, chloroform, ethanol and water extracts of the leaves of Melia azedarach L., Vitex negundo and Broussontia papyrifera and fruit of Datura anoxia were evaluated against Rhizopous niger, Fusarium chlamdosporum, Aspergillus niger, Stemphlium wallr and Hyloflora ramosa using clotrimazole as a reference standard. The antifungal activity was observed for ethanolic and hexane extracts of B. papyrifera. The chloroform extracts of M. azedarach L. was active against F. chlamdosporum (6.6 mm) and the chloroform extract of D. innoxia was inactive against all of the fungi tested. The water extract of D. innoxia showed highest activities against fungi S. wallr (4.95 mm) and minimum activity was observed for V. negundo against S. wallr (3.30 mm). Hexane extracts of B. papyrifera showed the highest antifungal activity against F. chlamdosporum (8.36 mm) and minimum was observed for V. negundo against R. niger (2.85 mm). The antifungal activities for all of the plants extracts were weak and it is not possible to use these plant extracts for the control of fungal diseases.
  Iqbal Zafar , Parvez Mohammad , Asadullah , Ismail Muhammad , Ahmad Bashir , Zakir Shahida and Gul Saima
  The crude ethanolic extract of leaves of Hedera helix L. was orally administered to the alloxan-induced diabetic rabbits. Significant hypoglycemic activity (p < 0.05) was observed after 90 min. of the administration of the extract. The acute hypoglycemic activity was studied by the oral administration of the extract with a dose of 250 mg Kg-1 body weight daily for seven days. It significantly decreased the concentration of glucose in blood (P < 0.01) without any visible physical-physiological changes. The oral administration of ethanolic extract has a beneficial effect on the diabetic state by lowering the blood glucose level through extra-pancreatic actions rather than by stimulated insulin release.
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