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Articles by Yun Den
Total Records ( 1 ) for Yun Den
  Chuanbin Zhu , Xingzhu Qi , Canding Wang , Wuzhou Yuan , Weiqi Zeng , Yuequn Wang , Zaochu Ying , Yun Den , Mingyao Liu , Yongqing Li and Xiushan Wu
  SVOPs are synaptic vesicle proteins that contain 12 transmembrane regions. Herein, we have isolated a novel human homologue of SVOP gene from a human brain cDNA library. This gene contains an open reading frame of 1646 nucleotides, coding for a protein with 548 amino acids. hSVOP is highly conserved in evolution across different species from C. elegans, fruit fly, mouse, to human. Northern blot analysis showed that it is expressed specifically in human brain. Transient transfection of COS-7 cells with hSVOP-EGFP demonstrates that hSVOP is located on cytoplasmic membrane and may be involved in material transfer between the synaptic vesicle and cytoplasm.
 
 
 
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