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Articles by Yinghui Li
Total Records ( 2 ) for Yinghui Li
  Gang Liu , Wenkai Ren , Dingding Su , Miaomiao Wu , Yinghui Li , Wei Luo , Xinglong Yu , Tiejun Li and Jun Fang
  This study was conducted to test the hypotheses that dietary L-arginine supplementation may enhance the immune responses and resulting in the clearance against PCV2 in experimentally infected mice. The measured variables include: the PCV2 virus load in liver, spleen, heart, lung, kidney, ovary and serum on 3rd, 5th, 7th, 9th and 11th day post infection (dpi); serum Interleukin-2 (IL-2), Interleukin-6 (IL-6), Interleukin-10 (IL-10), Interferon alpha (IFN-α), Interferon gamma (IFN-γ) and C-Reactive Protein (CRP) levels on 3rd, 5th, 7th, 9th and 11th dpi; serum Total Superoxide Dismutase (T-SOD) activity on 3rd, 5th, 7th, 9th and 11th dpi. Results showed that arginine supplementation could significantly increase the serum IL-2 levels on the 9th and 11th dpi; significantly increase the serum IFN-α and CRP levels on the 11th dpi; significantly increase the serum IFN-r levels on the 7th dpi and significantly decrease the serum IL-6 levels on the 9th dpi. Meanwhile, the PCV2 virus genome was detected sporadically. Collectively, dietary L-arginine supplementation had beneficial effects on the cytokines profile in the PCV2 infected mouse and maybe could delay the PCV2 replication and/or clear the PCV2 in mouse model.
  Wenkai Ren , Liming Zeng , Yinghui Li , Li Wu , Jieping Guo , Miaomiao Wu , Gang Liu and Yulong Yin
  Once a mammal infected by a microorganism an elaborate response will be generated that attempts to eliminate the infection agent. These responses contained innate immune responses and adaptive immune responses. Cytokines played a role in both innate and adaptive immune responses. Porcine circovirus type 2 was the causal agent of postweaning multisystemic wasting syndrome which was an economically important disease in pigs. Although, the interaction between immune responses and porcine circovirus was suggested as a determinant factor in the pathogenesis of postweaning multisystemic wasting syndrome, the reports about the cytokines profile in PCV2 infection were mixed and confused. Thus, a detailed review about this field was presented according to the literature and the lab’s conclusion.
 
 
 
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