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Articles by Yan Yan
Total Records ( 4 ) for Yan Yan
  Xiaoling Ding , Yan Yan , Chenghua Zhang , Yueyun Ding and Zongjun Yin
  In this study, leptin gene was chosen as a candidate gene to evaluate its effect on litter performance traits in four indigenous pig population of Anhui province in China. Two SNPs (U_66254 g.3469 T>C; g. 3714 G>T) in Exon 3 of leptin gene were demonstrated by PCR-SSCP and sequencing of PCR product. Litter performance traits including Numbers of Born Alive (NBA) of the first parity and latter parities were recorded in four pig breeds population. The further association analysis of the 2 SNPs with litter performance traits were conducted in four pig breeds population including 213 sows. Researchers found the 2 SNPs are significantly associated with litter performance traits. The effect of CC genotype of SNP (U_66254 g.3469 T>C) and TT genotype of SNP (U_66254 g.3714 G>T) were significantly higher than other genotypes in both litter traits (p<0.05). The study suggested that lepetin gene could be used for marker assisted selection program as a molecular genetic marker for litter sizes in Chinese indigenous pig breeding.
  Yan Yan and Xiaohong Hao
  A new method of robust reversible hiding algorithm is proposed in this study, which creates redundant space for information hiding by histogram shifting. Accommodation matrix used in this method reduced the modification extent of pixel values caused by histogram shifting and preserved the visual quality of stego-images. The design of interval region helped to realize the robustness of embedded information. Experiment results show that the new algorithm can not only extract secret information correctly and restore the original carrier image completely but also increase the resistance ability of secret information to some lossy processes.
  Xiaoliang Zhou , Kening Sun , Yan Yan , Shiru Le , Naiqing Zhang , Wang Sun and Peng Wang

The silver electric adhesive doped with Al2O3 ceramic particles is used as sealing material for planar solid oxide fuel cell (SOFC). The sealing temperature of this sealing material is 600 °C with the heating rate of 2 °C min-1, and the minimal leak rate ranges from 0.030 sccm cm-1 to 0.040 sccm cm-1. When doping 15 mass% Al2O3 ceramic particles into this sealing material, the thermal expansion coefficient of this material decreases from 20 ppm K-1 to 15 ppm K-1, which improves the thermal matching performance and the long-term stability of the material significantly. When using the gradient sealing method with the pure silver electric adhesive and the silver electric adhesive doped with Al2O3 ceramic particles to seal the interface of Ni-YSZ/SUS430 in the simulating cell, the minimal leak rate of 0.035 sccm cm-1 is obtained for the cell. Furthermore, the simulating cell sealed with the compound silver electric adhesive presents good heat-resistant impact ability. Therefore, this compound sealing technique is a very promising sealing method for SOFC.

  Guiqing Peng , Yan Yan , Chengliang Zhu , Shiqun Wang , Xiaohong Yan , Lili Lu , Wei Li , Jing Hu , Wei Wei , Yongxin Mu , Yanni Chen , Yong Feng , Rui Gong , Kailang Wu , Fengmin Zhang , Xiaolian Zhang , Ying Zhu and Jianguo Wu
  Borna disease virus (BDV) is one of the infectious agents that causes diseases of the central nervous system in a wide range of vertebrate species and, perhaps, in humans. The phosphoprotein (P) of BDV, an essential cofactor of virus RNA-dependent RNA polymerase, is required for virus replication. In this study, we identified the gamma-aminobutyric acid receptor-associated protein (GABARAP) with functions in neurobiology as one of the viral P protein-interacting cellular factors by using an approach of phage display-based protein-protein interaction analysis. Direct binding between GABARAP and P protein was confirmed by coimmunoprecipitation, protein pull-down, and mammalian two-hybrid analyses. GABARAP originally was identified as a linker between the gamma-aminobutyric acid receptor (GABAR) and the microtubule to regulate receptor trafficking and plays important roles in the regulation of the inhibitory neural transmitter gamma-aminobutyric acid (GABA). We showed that GABARAP colocalizes with P protein in the cells infected with BDV or transfected with the P gene, which resulted in shifting the localization of GABARAP from the cytosol to the nucleus. We further demonstrated that P protein blocks the trafficking of GABAR, a principal GABA-gated ion channel that plays important roles in neural transmission, to the surface of cells infected with BDV or transfected with the P gene. We proposed that during BDV infection, P protein binds to GABARAP, shifts the distribution of GABARAP from the cytoplasm to the nucleus, and disrupts the trafficking of GABARs to the cell membranes, which may result in the inhibition of GABA-induced currents and in the enhancement of hyperactivity and anxiety.
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