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Articles by Yadollah Pournia
Total Records ( 3 ) for Yadollah Pournia
  Mohsen Mohammadi , Ehsan Ghasemi , Hamid Mokhayeri , Yadollah Pournia and Hadis Boroun
  This study evaluated urine cultures and the antimicrobial resistance patterns of E. coli detected from urine culture. This study was performed on 520 hospitalized urine samples including 401 females and 119 males during one year (2008-2009) in Khorramabad City (West Iran). The urine cultures and antibiotic sensitivity tests based on Kirby-Bauer method were analyzed according to the antibiotic resistance pattern of each bacterium. A total of 520 urine samples were analyzed out of which 129 (24.8%) showed significant growth and 115 (89.1%) were gram-negative bacteria. The most frequently detected gram-negative bacterium was E. coli with 85 cases (73.9%). Urinary Tract Infection (UTI) was seen in 79.1% of the females as compared to 20.9% of the males (p<000.1). The most resistance rates for E. coli detected from urine culture were to ampicillin with 98.4% and to amoxicillin with 83.7%, respectively. The most antibiotic sensitivity rates were to amikacin with 93.3%, ciprofloxacin with 91.5%, nitrofurantoin with 89.8% and to nalidixic acid with (78.7%), respectively. Present findings demonstrated the significance of resistance increase of E. coli detected from urine culture to various groups of antibiotic drugs, caused by the irregular use of antibiotics.
  Hassan Ahmadvand , Ali Khosrobeigi , Leila Nemati , Maryam Boshtam , Narges Jafari , Reza Haji Hosseini , Yadollah Pournia , Hassan Ahmadvand , Ali Khosrobeigi , Leila Nemati , Maryam Boshtam , Narges Jafari , Reza Haji Hosseini and Yadollah Pournia
  The objective of the present study was to assess various antioxidative activities of Rosmarinic Acid (RA) and its effect on oxidation of Low Density Lipoprotein (LDL) induced by CuSO4 in vitro. It was demonstrated that RA was able to inhibit LDL oxidation and decrease the resistance of LDL against oxidation. Rosmarinic acid showed a decrease the formation of malondialdehyde (MDA) rate of 31.8, 36.7 and 50.3% at concentrations ranging from 100- 400 μM, respectively, against oxidation in vitro. The inhibitory effects of the RA on LDL oxidation were dose-dependent. Total antioxidant capacity of RA was 0.65±0.03 mmol of ascorbic acid equivalents/mmol RA. The RA showed remarkable scavenging activity on 2,2-diphenyl-picrylhydrazyl (DPPH) (IC50 0.06±0.004 μM). This study showed that RA is a potent antioxidant and prevents the oxidation of LDL in vitro and it may be suitable for use in food and pharmaceutical applications.
  Alireza Azargoon , Mojhgan Kaviani , Nahid Lorzadeh , Ezzatollah Rafiee Alavi , Mohammad Javad Tarrahi , Yadollah Pournia and Vahid Almasi
  The aim of this study was the assessment and comparison of serum prolactin level in the women with amenorrhea or oligomenorrhea and with normal mensturation period. In this cross sectional study, serum prolactin was assessed in two groups of 15-44 years women in Khorramabad. They did not use any drug, they were not pregnant or lactate and they had no chronic disease. One group had normal mensturation periods (control group) and another group had amenorrhea or oligomenorrhea. Fasting serum prolactin was assessed by Radioimmunoassay Method. The data were analysed with using SPSS software and Mann-Whitney test. Total 31 women with normal periods and 32 women with amenorrhea or oligomenorrhea were evaluated. Mean of serum prolactin in the control group was 538/6±351/6 and in the case group was 422/8±79/7. There was no significant difference between serum prolactin and development of amenorrhea or oligomenorrhea. In this study, there was no significant difference between serum prolactin and development of amenorrhea or oligomenorrhea. In the other hand, various conditions can develop pseudo hyperprolactinemia. Thus, researchers do not advise the routine evaluation of serum prolactin in the patients with amenorrhea or oligomenorrhea.
 
 
 
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