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Articles by Y.G. Dashe
Total Records ( 2 ) for Y.G. Dashe
  Y.G. Dashe , M.A. Raji , P.A. Abdu , B.S. Oladele and D. Olarinmoye
  Aeromonas species are increasingly incriminated in clinical cases in livestock and humans in Nigeria and the world at large. This investigative study was carried out between November, 2010 and October, 2011 in Jos, Nigeria to determine the isolation rate of Aeromonas species in clinically sick and apparently healthy commercial chickens. A total of 2000 postmortem samples consisting of bone marrow, heart, liver, lung and spleen (400 each) were aseptically collected from 400 clinically sick chickens suspected to be suffering from various clinical conditions and cultured for Aeromonas organisms. Four hundred oro-pharyngeal swabs were also collected from 400 apparently healthy chickens for bacteriological analysis. Swab from each sample was cultured on 7% defibrinated sheep blood and MacConkey. From the bacteriological cultures of the bone marrow, heart and liver of the sick chickens, a total 11 (0.5%) Aeromonas hydrophila isolates were identified by biochemical characterization and Macrobact™ test. Aeromonas organism was not isolated at all from the apparently healthy chickens. The co-occurrence of Aeromonas hydrophila with other pathogens in the sick chickens could have contributed to the observed exacerbation of clinical signs and mortalities in some of the investigated flocks during the study period.
  E.A. Ogunsan , A.A. Seawright , D.O. Ehizibolo , H.M. Tukur , M.S. Ahmed , Y.G. Dashe and M.Y. Sugun
  It has become apparent that inflammation provoked by injury to renal epithelial cells serves to amplify kidney injury and dysfunction in vivo Compounds including the sesquiterpene ketones generally believed to cause kidney injury by direct tubular toxicity or crystal nephropathy have been considered in different renal studies. The aim of this study was to highlight the histotoxicity of Deisopropylngaione (DIN) in mice. Ninety male quackenbush mice weighing between 30 and 35 g b.wt. were divided into five groups of fifteen mice per group and received 70, 98, 137, 192 and 268 mg kg-1 DIN intraperitoneally, respectively. Haematoxylin erosin (H and E) and Von Kossa stained histology slides showed proximal tubular necrosis and hyaline cast formation. Deposition of calcium salt in residual necrotic tubular epithelium was on the increase with increase in dose rate. Besides the pulmonary lesions seen in mice following intoxication by DIN, the kidney lesions were consistent with previous studies of these compounds in mice and similar to mercuric chloride poisoning in sheep.
 
 
 
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