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Articles by Xiaoyan Liu
Total Records ( 3 ) for Xiaoyan Liu
  Haiqing Yu , Chun Zhang , Zhiqiang Mei , Li Wang , Juan Li , Chenggang Duan , Xiaoyan Liu , Shu Gong , Lin Gan , Zhonghua Tao , Fuli Yao , Ye Yang , Chunyan Duan , Youping Liu , Chunyan Zhang , Chuanning Chen , Xiaoli Zheng , Hongxian Zhao , Jiyan Cheng , Xiaojun Tang , Yong Zhang , Yingxi Zhang and Junjiang Fu
  As a traditional medicinal herb in China, Penthorum chinense Push from Gulin county is regarded as genuine regional drug with better clinical effects. To discriminate the geographical origin of six P. chinense samples cultivated in three provinces, Randomly Amplified Polymorphic DNA (RAPD) analysis was carried out with an improved method to increase the resolution and production using 10 mer-random primers. Similarity index was ranged from 0.61 to 0.97, which demonstrated that samples from different localities displayed similar band patterns. However, based on the analysis of selected 13 primers, primers SBS-I9, SBS-I20 and SBS-Q9 produced distinguishable bands among Sichuan, Yunnan and Hubei P. chinense. T-test of mean S.I. values of six accessions demonstrated the significant differences between Luzhou or Sichuan samples and others. Cluster analysis indicated that cultivars with close geographic distributions were clustered together consequently. This suggested that there are RAPD site variations and local specialized genotypes among the six samples. The results indicated that RAPD analysis is effective in distinguishing the geographical origin of genuine regional drug P. chinense grown in Luhzou, Sichuan. The approach is a valuable tool to authenticate other morphologically similar herbal medicinal materials.
  Wei Zhang , Dongmei Zhu , Yang Tian , Min Tang and Xiaoyan Liu
  Background and Objective: Breviscapine considered to be an active ingredient of flavonoids and able to dilate the blood vessels, reduce vascular resistance, increase blood flow, improve microcirculation and suppress the aggregation of platelets. This study was assessed the therapeutic effect of breviscapine in combination with methylcobalamin in the management of diabetic peripheral nephropathy. Materials and Methods: The sample size of 300 subjects was taken and subdivided equally into 2 groups. Treatment group subjects were given a breviscapine oral dosage of 20 mg/day and a tablet of Vitamin B which further contained the 2 mg dL1 of folic acid and 1 mg dL1 of methylcobalamin. The therapy was given for continuous 12 months and followed up for 36 months. Another group had taken as a placebo group and received a dosage of 1 mg dL1 of methylcobalamin only. Glomerular filtration rate (GFR) was taken as primary level outcome. Results: Increased radionuclide GFR was 6.2 mL min1/1.73 m2 in the treatment group at 18 months and 10.8 mL min1/1.73 m2 at 36 months and decreased to -3.1 mL min1/1.73 m2 at 18 months and -5.7 mL min1/1.73 m2 at 36 months in the placebo group. So, a higher level of radionuclide GFR at 18 months and at 36 months was found in the treatment group when compared with the baseline level and placebo with significant p-value of less than 0.05. Conclusion: So it was concluded that the breviscapine improves the diabetic nephropathy sign and symptoms and also improves the quality of life of the subjects.
  Zhongquan Zhao , Xiaoyan Liu , Xugang Zhang , Yongju Zhao , Zhouquan Li and Jiahua Zhang
  Chongqing contains five goats breed resources representing special economic and ecological characteristics. These goat breeds’ characteristics were researched and genetic relationships with other goats in adjacent provinces were ensured by analyzed mitochondrial DNA (mtDNA) D-loop sequences. The results indicated the goat breed resources in Chongqing have especial production performance in growth, meat quality and fecundity. The five goats breeds in Chongqing had high mtDNA diversity but the differences among breeds were significant. The near genetic distance of Youzhou dark goat and Banjiao goat indicated Youzhou dark goat may be a subline of Banjiao goat. The results of this study contribute to the knowledge of the genetic structure and correctly protecting and utilizing these goat breeds.
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