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Articles by Wen-Fa Hu
Total Records ( 2 ) for Wen-Fa Hu
  Hua Tang , Xin-Sheng Liu , Yu-Zhen Fang , Li Pan , Zhong-Wang Zhang , Peng Zhou , Jian-Liang Lv , Shou-Tian Jiang , Wen-Fa Hu , Pan Zhang , Yong-Lu Wang and Yong-Guang Zhang
  The Foot-and-mouth Disease (FMD), which is the most devastating disease of livestock husbandry, drastically hinders the development of stock raising. At present the main FMD vaccine is still traditional inactivated vaccine, as its good performance in protective activity and immune efficacy, it is widely used in the world for preventing and controlling this disease, especially in developing countries. However, people have realized many disadvantages of inactivated vaccine. In order to resolve these problems, the scientists are conducting some new research about novel FMD vaccine to seek for more secure and effective vaccines. Nowadays, with the rapid development of molecular biology, researchers are paying high emphasis on novel FMD vaccines, such as, synthetic peptide vaccine, epitope-based vaccine, DNA vaccine, chimeric vaccine and so on. There is no doubt that these new-type FMD vaccines will make great contribution to the prevention and control of FMD. This study reviewed the international research progress on the traditional vaccines and novel vaccines of FMD.
  Hua Tang , Xin-Sheng Liu , Yu-Zhen Fang , Li Pan , Zhong-Wang Zhang , Peng Zhou , Jian-Liang Lv , Shou-Tian Jiang , Wen-Fa Hu , Pan Zhang , Yong-Guang Zhang and Yong-Lu Wang
  The Z-curve is a geometrical tool for visualizing and comparing genomes. Since, the curve contains the information carried by the given sequence, DNA sequences could be analyzed systematically. In this study, the ORF5 gene of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) was analyzed by the Z-curve method and the DNAstar (DNASTAR Inc.) computer programs. The results revealed by these two methods were identical. The phylogenetic tree is more digitized and the Z-curve method is more picturesque. It turned out to be that, the Z-curve method shows a widely application prospect in phylogenetic relationships analysis. However, the Z-curve method is still in its premature stage. Novel algorithms are expected to be exploited to extract more information involved in the Z-curves.
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