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Articles by Wei Wu
Total Records ( 4 ) for Wei Wu
  Wei Wu , Zhongzhao Zhang , Xuejun Sha and Chenguang He
  Some auto rate protocols at the MAC layer have been proposed to improve the throughput of Ad Hoc networks with multiple rates support at physical layer. However, all of them neglect the influence of network congestion. The network performance will deteriorate as a result of transmitting data to a congested node. In this study, an auto rate protocol based on congestion detection called auto rate based on congestion detection (ARCD) is proposed. In the ARCD protocol, congestion level is detected at the receiving nodes and fed back to the sending nodes along with the rate selection information and then the sending nodes transmit a limited number of back-to-back packets at appropriate rates. The simulation results show that the ARCD protocol can not only improve the throughput and packet delivery ratio of Ad Hoc networks by taking full advantage of channel condition, but also achieve hop-by-hop congestion control.
  Wei Wu , Jian-Guo Jiang and He Liu
  A simple equivalent circuit of multilevel inverters to predict the deviation of node voltages was analyzed and the capacitor voltage imbalance mechanism of diode clamped multilevel inverter was analyzed. An optimization algorithm of Space Vector Pulse Width Modulation (SVPWM) for capacitor voltage balance of diode clamped multilevel inverters is presented. This algorithm predicts the deviation of node voltages for different operation modes to develop an optimization algorithm to minimize the voltage deviation among different capacitors. This algorithm selects the best switch combinations during each switching cycle to reach node voltage balance. This algorithm is naturally applicable to inverters with an arbitrary number of levels. The simulation and experimental results verify the correctness of this algorithm.
  Yongfeng Sun , Tongao Yang , Jingtao Hu , Zhe Hao , Yujian Sui , Yingying Fu , Lu Chen , Haiyang Zhu and Wei Wu
  The muscular tissue of breast was dissected from 8 weeks old Jilin White goose in the present study. The big fragment PCR Method was used to amplify double-strand cDNA based on the SMART techniques for construction of a full-length cDNA library. After digestion with restriction endonuclease Sfi |, a modified vector of pBluescript II SK-plasmid with the adaptors containing Sfi |A and Sfi |B sites was used to recombine with the cDNA products amplified. The recombinants were cloned by transformation into competent Escherichia coli DH2α. A plasmid cDNA library with goose muscle was constructed. The results showed that the titer of the cDNA library was 1.01x106 pfu mL-1 and the percentage of recombinant clones was 97%. The length of most cDNA inserted was between 0.25 and 1.6 kb identified by gel electrophoresis after cDNA PCR amplification. The unigene ratio was 66.7% and the percentage of complete cDNA sequences was 80% by estimating from the 24 clones sequenced randomly. It is helpful to study muscle development of goose at molecular level in the future.
  Zhenghong Lin , Chan Gao , Yuanheng Ning , Xi He , Wei Wu and Ye-Guang Chen
  The canonical Wnt/β-catenin pathway plays a pivotal role in regulating embryogenesis and tumorigenesis by promoting cell proliferation. BAMBI (BMP and activin membrane-bound inhibitor) has previously been shown to negatively regulate the signaling activity of transforming growth factor-β, activin, and BMP and was identified as a target of β-catenin in colorectal and hepatocellular tumor cells. In this study, we provide evidence that BAMBI can promote the transcriptional activity of Wnt/β-catenin signaling. Overexpression of BAMBI enhances the expression of Wnt-responsive reporters, whereas knockdown of endogenous BAMBI attenuates them. Accordingly, BAMBI also promotes the nuclear translocation of β-catenin. BAMBI interacts with Wnt receptor Frizzled5, coreceptor LRP6, and Dishevelled2 and increases the interaction between Frizzled5 and Dishevelled2. Finally we show that BAMBI promotes the expression of c-myc and cyclin D1 and increases Wnt-promoted cell cycle progression. Altogether, our data indicate that BAMBI can function as a positive regulator of the Wnt/β-catenin pathway to promote cell proliferation.
 
 
 
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