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Articles by Warda S. Abdel Gadir
Total Records ( 3 ) for Warda S. Abdel Gadir
  Warda S. Abdel Gadir , Mohy Edeen , D. Abu Alazaim , Amel O. Bakhiet and I.M.T. Fadlalla
  This study was done on 40 Bovans-type chicks to investigate the possible toxic effects of the therapeutic doses of the antimalarial drugs, Quinine and Fansidar and their combined doses. After two weeks (adaptation period), the drugs were dissolved in distilled water in concentrations of 4.33 mg mL day-1 for Quinine, 4.19 mg mL day-1 for Fansidar and their mixture (4.33 mg Quinine plus 4.19 mg Fansidar) mL day-1 and given orally to Bovans chicks for two weeks. The effects on growth and tissues were investigated. After one week, there was no change in growth and at post-mortem examination, there was congestion of liver in all tested chicks and haemorrhage on the heart of chicks that had been given Fansidar. Serobiochemical changes were increase in the activities of AST, ALT and in concentration of albumin, uric acid, total protein and globulin and decrease in cholesterol levels. There were decreases in haemoglobin, PCV, MCV and MCH values. At the end of two weeks, there was depression in growth of tested chicks, degeneration of the liver of chicks that had been given Quinine and mixture of Quinine plus Fansidar and cardiac haemorrhage in chicks that had been given fansidar and or quinine plus fansidar with increases in AST, ALT activities and in total protein concentration with decreases in globulin levels and PCV values.
  Warda S. Abdel Gadir , Fathia Mohamed and Amel O. Bakhiet
  A study is described in which petroleum ether, ethanol and water extracts from Tamarindus indica ripe fruit and Piper nigrum seed in different concentrations (10-100%) were evaluated for their possible antibacterial activity against four standard pathogenic microorganisms, Staphylococcus aureus (gram-positive bacterium), Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi (gram-negative bacteria). The ethanol extract from T. indica fruit in different concentrations exhibited higher activity against all test bacteria than that from P. nigrum seed and that the activity is concentration-dependent. Petroleum ether extract from P. nigrum seed in different concentrations had no activity against E. coli, Ps. aeruginosa or S. typhi but had activity against S. aureus (inhibition zones 12-15 mm). Petroleum ether from T. indica fruit in concentrations of 10-100% had no antibacterial activity against E. coli and Ps. aeruginosa but the growth of S. aureus and S. typhi was only inhibited by 50% concentration of petroleum ether extract (inhibition zones, 5 mm). Water extract from T. indica fruit at 100% concentration produced inhibition zones at 14-15 mm for E. coli and Ps. aeruginosa, respectively, but had no activity against S. aureus or S. typhi. Water extract in 100% concentration from P. nigrum seed caused inhibition zones at 15 and 12 mm against S. aureus and S. typhi but had no activity against E. coli or Ps. aeruginosa. These findings were compared with those produced by gentamicin (10 μg), a reference antibiotic.
  Zeinab A.M. Elgadi , Warda S. Abdel Gadir and Hamid A. Dirar
  Fifty four raw milk samples were collected from cows (farms and venders), goats, ewes and camels of different areas of Khartoum state and microbiologically analyzed. Enumeration and isolation were carried out anaerobically at 37°C on MRS and M17 for lactococci and lactobacilli, respectively, aerobically on PDA at 25°C for yeasts and on nutrient agar for total viable count at 37°C. Sixty three MRS and M17 isolates and six PDA Isolates were purified and kept at 4°C for further identification. The presence of Lactic Acid Bacteria (LAB) and yeast was confirmed by colonial morphology, microscopy in addition to other biochemical tests. The ability of streptococci to ferment and assimilate sugars was carried out using the API kits. The results obtained showed that the milk samples contained lactobacilli and lactococci in the range of 3.50-6.30 and 3.48-6.21 log mL-1, respectively, yeast in the range of 2.00-3.95 log mL-1 and the total viable count in the range of 3.48-7.98 log mL-1. Lactic acid bacteria isolated from milk samples belonged to lactobacillus and streptococcus genera. The homofermentative lactobacilli from cows and camel milk were tentatively identified as Lactobacillus plantarum and Lb. acidophilus, whereas the hetero fermentative ones from cows, goats and ewes milk were found to be Lb. fermentum. The homofermentative streptococci isolated from all milk samples were tentatively identified as Streptococcus cremoris and Streptococcus lactis, whereas the only heterofermentative strain from camel milk was found to be Leuconostoc lactis. Yeasts which were only isolated from cow`s milk, were identified as Debaryomyces hansenii (4 strains), Kluveromyces lactis (one strain) and Saccharomyces rouxii (one strain).
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