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Articles by Walaa A. Moselhy
Total Records ( 2 ) for Walaa A. Moselhy
  B.R. Abdel- Halim , A.A. Khalaf , Walaa A. Moselhy and Walaa M.S. Ahmed
  Objective: The current study was conducted to investigate the protective effect of selenium preparations against the reproductive toxicity of bisphenol A. Materials and Methods: Sixty adult Albino male rats (aged from 2-3 months and average weight 150-180 g) were used and they were randomly divided into sex equal groups. Group I served as control, group II were orally administered BPA in a dose level of 1/10 LD50 (150 mg kg–1 b.wt.) for 8 successive weeks, group III were gavaged with BPA plus ionized selenium in a dose level of (3 mg kg–1 b.wt.), group IV animals in this group orally given BPA plus nano-selenium particles in a dose level of (2 mg kg–1 b.wt.) and groups V and VI were gavaged with both IS and NSP with previous doses. All data were analyzed using one way analysis of variance (One way ANOVA) followed by Duncan test using SPSS version 16.0 statistical software. Results: The obtained results revealed that exposure to BPA significantly induce testicular damage observed in testicular weight, sperm morphology and significant decrease in testosterone level and increase in percent of sperm abnormalities. Ultrastructural examination of testis revealed that both selenium preparations reduced the testicular damages induced by BPA. Conclusion: High concentrations of Se in testis and epididymes indicate its importance for the processes of production and maturation of spermatozoa. Nano-Se has lower toxicity and possesses equal efficacy in increasing the activities of selenoenzymes. It can serve as an antioxidant with reduced risk of Se toxicity and a potential chemopreventive agent if the induction of GST by Se is a crucial mechanism for its chemopreventive effect.
  Arafa M.S. Meshref , Walaa A. Moselhy and Nour El-Houda Y. Hassan
  Aluminium is non-essential element for humans and is considered to be a toxic metal. The present investigation was carried out to determine aluminium concentrations in milk and milk products, to estimate the intake of aluminium via consumption of milk and dairy products and to investigate the leachability of aluminium from utensils into milk products during processing and storage. A total of 85 milk and milk products samples were collected from farms, individual farmers and dairy shops in Beni-Suef governorate, Egypt. Mean aluminium concentrations in farm milk, market milk, kareish cheese, yoghurt and rice pudding were 19.93, 107.32, 52.36, 4.19 and 80.97 ppm, respectively. Aluminium intake through milk and milk products consumption was calculated to be 246.72 mg week–1 which corresponds to 205.5% of the PTWI. Processing and storage of milk in aluminium containers also raise aluminium content significantly. The results indicated the advantage of using stainless steel over aluminium utensils for processing and storage of milk products, especially those acidic in nature.
 
 
 
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