Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
Articles by W.X. Fu
Total Records ( 2 ) for W.X. Fu
  Y. Liu , X. Lu , J.G. Xu , Z.Q. Weng , W.X. Fu , Y.R. Luo , X.Y. Niu and Q. Zhang
  Interferon regulatory factor 7 (IRF-7) plays a crucial role in virus-induced activation of interferon-alpha/beta transcription and innate immunity. In order to evaluate its effect on cytokine traits in pig, IRF7 gene was chosen as a candidate gene to investigate in pig populations. SNP was identified by sequencing and PCR-RFLP method. Cytokine traits including IFN-γ and IL10 concentration in serum were measured when pigs were at the age of 20 and 35 days, respectively. The further association analysis between SNP genotypes and cytokine traits were conducted in three breeds including Large White, Landraces and Songliao Black, the later one is Chinese indigenous breed. The results indicated that the SNP of IRF7 gene had a highly significant effect on the level of IL10 (day 20) (p = 0.047), IFN-γ (day 35) in serum (p = 0.031) and the ratio of IFN-γ to IL10 (day 35) in serum (p = 0.035). The study suggested that IRF7 gene could be regarded as a molecular marker gene for genetic selection of cytokine traits in the further disease resistance breeding.
  Y. Liu , Y.R. Luo , X. Lu , X.T. Qiu , W.X. Fu , J.P. Zhou , X.Y. Liu , Q. Zhang and Z.J. Yin
  In this study, haematological traits, lysozyme concentration and T lymphocyte subpopulation as markers of innate immunity were detected and compared among Landrace, Large White and a chinese indigenous breed, Songliao Black pig. The animals were of the same age and kept under the same environmental conditions to reduce non-genetic variation in immune traits; they were all apparently healthy and were vaccinated by CSF live vaccine at 21 days of age. Except LY%, MO%, CD4CD8% and RDW, the other detected immune traits were significant difference between before (20 days) and after vaccination (35 day). While the values of MCV, MCH, MCHC, MO%, CD4+CD8+% and CD4+CD8+/CD4CD8+ values decreased after vaccination, the others increased. The values of WBC, GR, LY, MO, CD4+CD8% and CD4+CD8+% were significant difference among Large White, Landrace and Songliao Black pig (p<0.05). Our analysis confirms that Songliao Black pig has better innate immune level than Landrace and Large White. The animal resource population was suggested to be appropriate to investigate further the QTL and genes contributing to differences on these innate immune traits in pigs.
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility