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Articles by Van Huy Nguyen
Total Records ( 3 ) for Van Huy Nguyen
  Thanh Loan Pham , Van Huy Nguyen , Thi Le Thu Hoang , Thi Tam Tien Ha , Chi Nghia Phan , Xuan Duong Vu , Mai Thao Hoang , Thi Thanh Doan Ha and Thi Ngoc Diep Tran
  Background and Objective: Rehmannia glutinosa Libosch. is an important medicinal plant, used widely in folk remedies for daily health care in Vietnam. This study aimed to evaluate the effect of nitrogen and phosphorus fertilizers and plant spacing on the growth, yield and quality of R. glutinosa roots. Materials and Methods: The experiment consisted of two factors: Factor A: Nitrogen (5 levels), phosphorus (5 levels) and Factor B: plant spacing (3 levels). Experiments were laid out in randomized complete block design (RCBD) with three replications. Results: The results show that nitrogen and plant spacing significantly affected the vegetative growth of R. glutinosa in which N application of 240 kg ha1 and plants arranged in 20×30 cm spacing brought the highest growth characters while P application showed little difference in canopy diameter. N and P application and their interaction with spacing significantly influenced the yield and quality of roots in which N4 (180 kg N ha1)×S3 (20×30 cm) and P4 (120 kg P ha1)×S3 (20×30 cm) produced the highest yield and quality of roots. Conclusion: The current study provides further insights into the effectiveness of chemical fertilizer and plant spacing on the growth and development of R. glutinosa. Further evaluation of wider spacing and changes of bioactive compounds under various conditions would be necessary for medicinal plant utilization.
  Phi Bang Cao , Van Huy Nguyen , Thi Man Le , Thi Lan Huong Phung , Xuan Duong Vu and Thi Bich Ngoc Chu
  Background and Objective: Salicylic Acid (SA) is a plant hormone that plays a key role in regulating many physiological processes in plants, including seed germination, plant growth, photosynthetic efficiency, crop yield, flowering and senescence. This study aimed to investigate the physiological responses of Chrysanthemum variety “Mai Vang” to different concentrations of SA (0, 0.5, 1.0, 1.5 and 2.0 mM). Materials and Methods: The Chrysanthemum were treated by various concentrations of SA (0.5, 1.0, 1.5 and 2.0 mM), water treatment (SA0) was considered as control. The experiment conducted in a complete randomized design with a total of five treatments, each plot consisted of 15 plants. Duncan’s multiple range test was being used for statistical analysis at the 5% level of significance (p = 0.05). Results: The SA treatments affected the content of photosynthetic pigments, proline and malondialdehyde (MDA) in leaves as well as anthocyanin in florets. Generally, SA treatments at a concentration of 0.5 and 1.0 increased the content of chlorophylls and carotenoids while decreasing the content of MDA compared to water treatments. In contrast, SA1.5 and SA2.0 treatments decreased the content of these pigments while enhancing the accumulation of MDA compared to control. All SA treatments displayed higher content of proline in leaves than control. Also, plants treated by SA at 0.5 and 1.0 mM exhibited higher maximum quantum yield of photosystem II (Fv/Fm) value than untreated and 1.5 and 2.0 mM of SA treated ones. Conclusion: The present study provides further insight into the effectiveness of SA on the physiological characteristics of Chrysanthemum “Mai Vang”. Especially, SA at 1.0 mM had the maximum positive effect on the content of photosynthetic pigments, proline, anthocyanin and Fv/Fm index. Moreover, SA1.0 treatments exhibited a significant decrease in MDA content compared to control.
  Thanh Loan Pham , Van Huy Nguyen , Thi Tam Tien Ha , Thi Le Thu Hoang , Chi NghiaPhan and Thi Quyen Nguyen
  Background and Objective: Celastrus hindsii Benth. has been used for generations in Northern Vietnam, for the treatment of disease relating to ulcers, tumors and inflammation without safety evidence. This study's goal is to evaluate the safety of the aqueous extract of leaves of C. hindsii through an acute and semi-chronic toxicity oral administration. Materials and Methods: In the acute study, a single oral dose (1000, 3000, 5000 and 15000 mg kg1) of the aqueous of C. hindsii extract were administered to mice and observed for seven days. In the semi-chronic study, rabbits were administered daily with 1000 and 3000 mg kg1 of the extract for 35 days. Hematological and biochemical analyzes were carried out on blood and serum samples collected. Results: A single oral administration of 15000 mg kg1 per day for white mice did not determine the LD50 dose. At doses of 1000 and 3000 mg kg1 for 35 days, the extract from C. hindsii induced neither clinical symptoms of rabbits nor significant changes in hematological parameters such as; total blood cells, hemoglobin concentration, white blood cells and platelets. The quantity of aspartate transaminase (AST or GOT), alanine transaminase (ALT or GPT) of rabbits in the experimental and control group did not differ (p> 0.05). Liver and kidney organizations were also not affected adversely. Conclusion: The results indicate that the oral administration of C. hindsii extract did not produce any significant toxicity in mice, therefore, it is recommended to be used safely for traditional medical practices and modern pharmaceutical applications.
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