Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
 
Articles by V. Gupta
Total Records ( 5 ) for V. Gupta
  A. Pandey , M. Kamle , L.P. Yadava , M. Muthukumar , P. Kumar , V. Gupta , M. Ashfaque and B.K. Pandey
  In the context of the GM food regulations crop improvement via transgenic technology is a new stage of introducing novel food which supercedes over the conventional breeding. It was analyzed that worlds hunger, malnutrition problems, environmental pollution and phytoremediation in agriculture are the challenges for scientist as well as governments those can be combated by application of genetic engineering in crops. Genetically modified microbes/plant/animals or GM microbes/plant/animals results from modification in the genetic make-up of microorganisms, plants and animals using recombinant DNA technology to improve the nutritional requirement, disease resistant traits, increased production and medicinal properties. In many instances, these modification processes represent faster, more efficient mechanisms for achieving changes than traditional breeding. However, a wide variety of modifications are possible through genetic manipulation and the potential for the introduction of toxic compounds, unexpected secondary effects and changes in nutritional and toxicological characteristics may give rise to safety concerns about GM crops. Thus, generation of GM food explores new vistas for future food requirement but the assessment of policy regarding environmental risks is also to be concerned.
  A. Pandey , M. Kamle , L.P. Yadava , M. Muthukumar , P. Kumar , V. Gupta , M. Ashfaque and B.K. Pandey
  .
  V. Gupta , S.K. Shukla , S.M. Shrivastava , S. Shukla , K. Kumar , D.P. Saxena , B. Shrivastava and M. Chaudhary
  The aim of this research was to study the influence of formulation parameters in the preparation of sustained release aceclofenac loaded PLGA microspheres by emulsion solvent diffusion technique. The methods used in this components and their concentration necessary for organogels formation were evaluated using phase diagram Solubility of aceclofenac was determined, Characterization of Poly (DL-lactide)-co-glycolide (PLGA) polymer, solubility assessment of aceclofenac, drug-excipients compatibility studies, in vitro analytical method development , preparation of aceclofenac-loaded PLGA microspheres, characterization of the formulations. Prepared microspheres were optimized and evaluated for different parameters and best formulation was subjected to in vitro drug release studies. The prepared microspheres were white, free-flowing and almost spherical in shape. In vitro drug release studies were carried out up to 24 h in three different pH media, i.e., 0.1 N HCl (pH 1.2), phosphate buffer (pH 6.8) and phosphate buffer (pH 7.4). The drug-polymer concentration of dispersed phase influences the particle size and drug release properties. In nut shell it may be concluded that sustained release aceclofenac microspheres can be successfully prepared and used parenterally with increased therapeutic value and reduced side effects.
  A. Baghel , D.S. Rathore and V. Gupta
  In that study, Mimosa pudica linn was tested for diuretic activity using the lipschitz test. The ethanolic and aqoues extract of Mimosa pudica Linn. was studied at two dose level 100 and 200 mg kg-1 b.wt. Furosemide (20 mg kg-1 b.wt.) was used as standard drug in a 0.9% saline solution. Urine volumes were measured for all the groups up to 5 h. The ethanolic extract of Mimosa pudica linn was exhibited significant diuretic activity at doses of 100 and 200 mg kg-1 b.wt. by increasing total urine volume and ion concentration of Na+ k+ and Cl¯.
  D.P. Saxena , S.K. Shukla , K. Kumar , R. Saxena , S. Saxena , S. Shukla , V. Gupta , R. Stephen , H. Kumar and L. Kumar
  The aim of this study was to test the in vitro antiplasmodial effect of extract and different fractions of Diospyros melanoxylan. Diospyros melanoxylon (Barks) are collected from the lower forest of Uttaranchal, which is identified by the local people. Plant materials are known as source of new antimicrobial agents, as a result search has been to discover new antibacterial drugs of plant origin. Six of eight methanolic extracts were found to have significant activity, in vitro anti-plasmodial effect of the water and ethanol extract of IC50 value is ranging from (IC50 = 116±9.19 and IC50 145±140 μg mL-1) and (IC50 = 35±0.0 and IC50 47±4.24 μg mL-1) of D. melanoxylon against chloroquine resistant and susceptible variety of Plasmodium falciparum. Least phytochemicals was observed in case of petroleum ether. These results, so obtained demonstrate the broad spectrum activity of D. melanoxylon bark extracts which may be useful in treatment of various microbial infections. Extracts of three of the four species of Indian Diospyros tested in this study showed antiplasmodial activities, with the best activity shown by D. melanoxylon. This species especially is worthy of further investigation to determine which of its constituents are responsible for the activity.
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility