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Articles by U.Z. Faruk
Total Records ( 3 ) for U.Z. Faruk
  S.W. Hassan , R.A. Umar , H.M. Maishanu , I.K. Matazu , U.Z. Faruk and A.A. Sani
  The effect of solar, sun and oven drying on the nutrients and non-nutrients composition of leaves of Gynandropsis gynandra was determined. Ash content of sun (3.14±0.09%), solar (3.16±0.03%) and oven (3.30±0.08%) dried samples were significantly (p<0.05) increased compared to fresh samples. All the drying methods were found to significantly (p<0.05) lower moisture, carbohydrates and protein. However, crude fibre content was significantly (p<0.05) increased with drying method. Drying method, with exception of oven drying, did not significantly (p>0.05) lower lipid content. Significant (p<0.05) increases of mineral elements upon drying with exception of sodium were observed. Alkaloids, tannins, saponins, saponins glycosides, flavonoids and volatile oils were detected in fresh and dried samples. These phytochemicals detected were found to decrease upon drying to trace amounts. Solar and oven drying were found to significantly reduce acid value from 3.91±0.31 to 1.66±0.06 and 2.69±0.33%, respectively. Solar drying may be the preferred method of drying the leaves of Gynandropsis gynandra as it is faster, more hygienic and preserves the nutrients better.
  S.W. Hassan , R.A. Umar , M. Lawal , L.S. Bilbis , B.Y. Muhammad , U.Z. Faruk and A.A. Ebbo
  The alkaloidal composition, histopathological and toxicity studies of alkaloid and aqueous ethanol extracts of Boscia angustifolia on biochemical indices of kidney and liver functions in rats were studied. The amount of alkaloids detected in 50 g powdered root extract of the plant was 11.44% (w/v). Renal and liver indices were significantly (p<0.05) altered at higher doses of 703.60, 1125.70 (alkaloidal extract), 839.30 and 1342.80 mg kg-1 body weight (aqueous ethanol extract). The aqueous ethanol and alkaloidal root extracts produced histopathological lesions of the liver and kidney at higher doses. These lesions include perivascular cuffs, protein cast, infiltration (kidney) and slight infiltration and perivascular cuffs (liver). There was a significant (p<0.05) dose dependent decrease in weight in the rats given higher doses of the aqueous ethanol and alkaloidal root extracts of Boscia angustifolia. The use of this plant is associated with some levels of organ toxicity.
  S.W. Hassan , F.L. Bilbis , M.J. Ladan , R.A. Umar , S.M.Dangoggo , Y. Saidu , M.K. Abubakar and U.Z. Faruk
  The aqueous and organic solvents extracts of leaves, stem barks and roots of Calotropis procera were screened for antifungal (agar dilution method) and phytochemical properties. Organic solvents extracts of the stem bark significantly (p<0.05) inhibited growth of Trichophyton rubrum and Microsporum gypseum. The petroleum ether (PE) extract however was significantly (p<0.05) active on only Trichophyton rubrum at concentrations ranging from 0.66 to 5.33 mg mL-1. All the leave extract fractions completely inhibited the growth of the tested organisms. The roots fractions of hexane (HX) and PE extracts showed significant (p<0.05) growth inhibitions of Microsporum gypseum and Aspergillus niger. All the aqueous extract fractions of the plant parts showed complete growth inhibition of all the tested organisms. Alkaloids, flavonoids, tannins, steroids, triterpenoids, saponins and saponin glycosides were detected in the leaves and roots extract fractions, with only flavonoids, triterpenoids and saponins in the stem bark extracts. The results obtained lend scientific credence for the use of the plant against fungal diseases.
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