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Articles by TANG Bo
Total Records ( 1 ) for TANG Bo
  TANG Bo , XILIN Gao-wa , FU Ben-dong , DU Chen-guang and CAO Gui-fang
  The epithelial cell of the Mongolian sheep's fallopian tubes were cultured as in vitro model, different concentrations of progesterone (10-6, 10-7, 10-8, 10-9 and 10-10 mol/L) were added in the culture, and then the relative expressions of sheep -defensin-1 (sBD-1) mRNA were surveyed by real time PCR. The results showed that, compared with the control group, the relative expressions of sBD-1 mRNA added with 10-6 and 10-7 mol/L progesterone were significantly higher (P<0.05), and those of 10-8 and 10-9 mol/L groups were remarkably higher (P<0.01). However, there was no significant difference between 10-10 mol/L group and control. Among groups added with progesterone, the sBD-1 mRNA expressions of 10-8 and 10-9 mol/L groups were markedly higher than that of 10-10 mol/L group (P<0.01), but there was no difference among other added groups. The results indicated that progesterone promoted the relative expression of sBD-1 mRNA in the epithelial cell of the fallopian tubes within the indicated concentrations (10-9-10-6 mol/L). And the relative expression of sBD-1 mRNA was varied with the different concentrations of progesterone. In conclusion, the expression of -defensin was related to progesterone in female reproductive tract.
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