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Articles by T. Zhang
Total Records ( 4 ) for T. Zhang
  C. Nathanailides , T. Chanzaropoulos , A. Barbouti , C. Perdikaris and T. Zhang
  The motility, fertilising ability and DNA integrity of freeze-thawed goldfish sperm was evaluated using computer-aided sperm motility analysis and the comet assay. The results indicate that sublethal effects during the freeze-thawing procedure compromised sperm fertilising ability, DNA integrity, velocity linearity and the duration of swimming. Compared to 10% Ethylene glycol (EG), 5% and 10% Egg yolk (EY) and DMSO treated sperm exhibited higher percentage of motile sperm and higher path velocity (VAP); straight-line velocity (VSL) linearity (LIN), DNA integrity and fertilising ability. There was a low but significant (r = 0.67, p<0.05) correlation between DNA integrity and the maximum Duration of Forward Progressive Swimming (DFPS) ability of cryopreserved goldfish sperm. DNA integrity and to a lesser degree the simple assessment of the DFPM of thawed sperm may be reliable indicators of sperm integrity for the development and the rapid assessment of fish sperm cryopreservation protocols.
  X. Yu and T. Zhang
  This study considered a model of an Ant Colony Optimization (ACO) algorithm for the general combinatorial optimization problem. The model proved that it can converge to one of the optima if only this optimum is allowed to update the pheromone model and that it can not converge to any of the optima if two or more optima are allowed. The iteration complexity of the model can be computed easily. And then a lower bound of time complexity of a real ACO algorithm for the general combinatorial optimization problem can be obtained.
  C. Ju , B. Xu , Y. Lu , X.J. Mo , T. Zhang , S.B Chen , F. Liu , S.J. Cui , W. Liu , J.H. Chen , Z. Feng , J.X. Peng and W. Hu
  Schistosomiasis ranks as the second most serious parasitic disease worldwide after malaria. More than 250 million people are infected with schistosomes in the tropics or subtropics. The treatment and control of schistosomiasis which is a major neglected tropical parasitic disease, depends almost exclusively on chemotherapy with Praziquantel (PZQ). Current serologic diagnostic assays have shown that schistosome specific antibodies in human serum may remain for at least 1 year after cure. Repeated administration of PZQ for a long time might induce drug resistance to the parasite which is a big challenge for strategizing for the prevention and control of schistosomiasis. As schistosome eggs represent the most pathogenic form causing the disease, it is essential to determine if and how the level of antibodies against schistosome Soluble Egg Antigens (SEA) is affected by PZQ treatment. In this study, researchers carried out an immunomic analysis to profile Schistosoma japonicum SEA reacting with pooled human serum samples of pre and post treatment with PZQ by two dimensional electrophoresis combined with Western blotting. A total of 67 protein spots that were serologically recognized by serum samples were successfully subjected to mass spectrometric analysis. Of them, 37 different characterized proteins were successfully identified. Furthermore, of 67 protein spots, the reactivity of 49 protein spots to sera was reduced 20 weeks after PZQ treatment whereas only 5 spots showed increases in the intensity of recognition by post treatment sera. The present study suggested that chemotherapy with PZQ mainly affects the intensity of serological recognition of S. japonicum SEA. The immunomic proteins that were identified may facilitate a better understanding of the egg induced pathogenesis of schistosomiasis and host-parasite interplay and may provide potential targets for the diagnosis and evaluation of treatment for the disease as well.
  J. Xie , N. Imanishi , T. Zhang , A. Hirano , Y. Takeda and O. Yamamoto

LiCoPO4 thin films were deposited on Li1+x+yAlxTi2-xSiyP3-yO12 (LATSP) solid electrolyte by radio frequency magnetron sputtering and were characterized by X-ray diffraction and scanning electron microscope. The films show a (1 1 1) preferred orientation upon annealing and are chemically stable with LATSP up to 600 °C in air. An all-solid-state Li/PEO18-Li(CF3SO2)2N/LATSP/LiCoPO4/Au cell was fabricated to investigate the electrochemical performance and Li-ion chemical diffusion coefficients, , of the LiCoPO4 thin films. The potential dependence of values of the LiCoPO4 thin film was investigated by potentiostatic intermittent titration technique and was compared with those of the LiFePO4 thin film. These results showed that the intercalation mechanism of Li-ion in LiCoPO4 is different from that in LiFePO4.

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