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Articles by T. Thomas
Total Records ( 2 ) for T. Thomas
  M Mosavel and T. Thomas

The prevailing paradigm of health exchange within the family is for health advice to flow from parent to child. Consistent with this pattern of exchange, most research has focused on the one-directional influence of the parent on the child and there is thus an absence of literature that explores the ability of adolescents to influence their parents’ health behaviors. This qualitative study addressed this gap by exploring the feasibility of daughters providing health advice to their mothers. Twelve focus groups were conducted with 78 African–American and Latina daughters between the ages of 12 and 17 from low-income neighborhoods in a Mid-Western city in the United States. This study utilized a grounded theory approach to examine the focus group data. The findings indicate that many daughters report that they are already giving their mothers a wide spectrum of advice, including health advice. Differences were found in the reported willingness of African–American daughters when compared to Latina daughters to provide their mothers with specific cancer advice. These data suggest that some of these daughters have the potential to be valuable health education conveyers in the family.

  T. Cherian , S. Singh and T. Thomas
  The aim of the present study is to evaluate the role autonomic receptors in initiating neurogenic contractions and the role of post-synaptic alpha adrenergic receptors in controlling the contractility of the ovine ureter. Isolated sheep ureter strips were studied to clarify the autonomic receptor functions by investigating the actions of selective agonists and antagonists. Noradrenaline shows a well pronounced excitatory effect on uretero-pelvic and vesicular regions which can be blocked by phenoxybenzamine, a non-selective alpha adrenergic receptor blocker. Selective blockade of alpha-1 receptors with prazosin did not inhibit the action noradrenaline but yohimbine, a selective alpha-2 receptor blocker, abolished the effect of noradrenaline in pelvic, proximal and vesicular regions of the ureter. Selective blockade of alpha-1 receptors with prazosin inhibit the action of noradrenaline all regions of the ureter except pelvic, proximal and vesicular regions of the ureter. Clonidine, a selective alpha-2 agonist, produced a significant contractile effect on the ureter in the pelvic, proximal and vesicular regions but not significant effect on the rest of the regions of the ureter. Phenylephrine, a selective alpha-1 receptor agonist show remarkable contractile effect on all parts of the ureter except the pelvic, proximal and vesicular regions. High intensity, high frequency, short duration stimuli applied on spontaneously contracting ureteral segments show enhancement of contraction which can be blocked by pretreating the preparation with phenoxybenzamine and tetrodotoxin (TTX). This study suggests that post-synaptic receptors responsible for the mediation of the stimulatory action of noradrenaline are of the alpha-2 subtype in the pelvic, proximal and vesicular regions of the ureter and alpha-1 in the rest of the regions.
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