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| Articles
by
T. Begum |
Total Records (
2 ) for
T. Begum |
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A. Sarwar
,
M.S. Rahman
,
T.B. Huq
,
K. Biswas
,
M.I. Hussain
,
J.F. Chaity
,
T. Begum
,
Md. E. Haque
,
A. Islam
and
Mst. M. Begum
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Background and Objective: To compare the prevalence of acute vomiting between patients receiving cisplatin as monotherapy or cisplatin in a combination regimen. Materials and Methods: The study was conducted at Delta Hospital Dhaka on a total of 70 patients (44 male and 26 female). The patients received either cisplatin alone or cisplatin with the following chemotherapeutic agents-docetaxel and 5 fluorouracil, docetaxel, etoposide, doxorubicin and capecitabine. The study was conducted in patients receiving chemotherapy for a total of the first 3 cycles. The patients were told to record the number of episodes of vomiting they experienced during the first 24 h after chemotherapy at each cycle. All 70 patients received prechemotherapy antiemetics a combination of 5HT3 receptor antagonist (ondansetron or palanosetron) and dexamethasone prior to chemotherapy. Results: In patients receiving the combination chemotherapy of cisplatin+docetaxel+5 FU experienced the lowest incidence of acute vomiting and cisplatin+capecitabine receiving patients experienced highest incidence of acute vomiting. All the other combination therapy resulted in emesis comparatively similar to that of cisplatin. In all the regimens except for cisplatin+etoposide the percentage of patients experiencing acute vomiting reduced along with progressive cycles. Conclusion: When cisplatin is given in combination regimen except for the combination regimen of cisplatin+capecitabine there is no significant increase in emesis between patients receiving cisplatin alone or in combination therapy. |
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M. Alauddin
,
T. Parvin
and
T. Begum
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The mechanism of clouding of nonionic surfactant and
the effect of additives on the cloud point has been investigated. The
cloud point temperature of Triton X-100 solutions in the concentration
range 1-10% and the cloud point behavior of 4 and 10% Triton X-100 solutions
in the presence of some aliphatic alcohols and alkanes of different concentrations
have been studied. A sharp rise in cloud point of aqueous solutions of
Triton X-100 occurs with increasing surfactant concentration beyond 4%.
A small but significant decrease in cloud point is observed upon the addition
of hexane, heptane, octane and decane to 4 and 10% Triton X-100 solutions.
The alkanes of higher chain length are more effective in depressing the
cloud point and the extent of depression follows the order: decane>octane>heptane>hexane.
Lower alcohols enhance the cloud point while the higher alcohols including
butoxyethanol depress the cloud point. The depression of cloud point of
Triton X-100 solutions containing same amount of alcohols follows the
order: decanol>octanol>heptanol>hexanol>butanol. |
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