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Articles by Syam Mohan
Total Records ( 2 ) for Syam Mohan
  Siddig Ibrahim Abdel-Wahab , Ahmad Bustamam Abdul , Hew Kim Fong , Syam Mohan , Manal Mohamed Elhassan , Adel Sharaf Al-Zubairi and Abdelbasit Adam Mariod
  The aim of the present study, is to evaluate the antimicrobial, phenolic content and free radical scavenging properties of the dichloromethane extract of Goniothalamus umbrosus leaves. The antimicrobial activities were evaluated using 2 Gram-positive bacteria, Methicillin Resistant Staphylococcus aureus (MRSA) and Bacillus subtilis B 29 and 2 Gram-negative bacteria, Pseudomonas aeruginosa 60690 and Salmonella choleraesuis using disc diffusion method and compared alongside to streptomycin. Antioxidant effect and total phenolic content of the extract were also measured by DPPH assay and Folin-Ciocalteu reagent, respectively. The results have concluded that the extract explicit a broad spectrum antimicrobial activities against all tested bacteria. However, antioxidant activity is significantly different from the activity of the positive control, BHT. Accordingly, the total phenolic compounds were also, observed to be correlated positively with the low antioxidant activity revealed by the extract. As a conclusion, the promising broad spectrum antimicrobial activities of the dichloromethane extract of the leaves of G. umbrosus might be due a different chemical constituent (s) since, the phenolic compounds were not found richly in the extract. Further, phytochemical investigations are currently conducted to explore the active ingredients as new substance (s) in the pharmaceutical industry.
  Syam Mohan , Ahmad Bustamam Abdul , Siddig Ibrahim Abdel Wahab , Adel Sharaf Al-Zubairi , Manal Mohamed Elhassan and Mohamed Yousif
  The antioxidant and antibacterial activity of different extracts from of Typhonium flagelliforme (L.) Blume leaves (family: Araceae) commonly called ‘Rodent Tuber’ was assessed towards different antioxidant models as well as in selected bacteria. None of the extracts showed significant activity against the selected strains. The only exception is hexane extract (2.0±0.15 mm diameter) against Pseudomonas aeruginosa. The positive control, Streptomycin had shown zone of inhibition of 20±1.5, 20±1.3, 23±1.5 and 23±1.0 mm in Methicillin Resistant Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella choleraesuis and Bacillus subtilis, respectively. All the extracts were subjected to screening for their possible antioxidant activity. Two complementary test systems, namely DPPH free radical scavenging and total phenolic compounds, were used for the analysis. The results showed that the inhibitory activity of Dichloromethane (60.7±3.2%) and Methanol (60.1±2.3%) extracts were comparatively commendable inhibition capacity when compared to the positive control BHT (95.3±1.3%). The total phenolic content of Methanol extracts (5.69±0.15 GAE mg g 1 extract) was superior to all other extracts, followed by dichloromethane and ethyl acetate. Considering all the results collectively T. flagelliforme appears to be a promising plant demonstrating antioxidant activity that requires further investigation.
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