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Articles by Suzita Mohd Noor
Total Records ( 2 ) for Suzita Mohd Noor
  Fouad Hussain , Mahmood Ameen Abdulla , Suzita Mohd Noor , Salmah Ismail and Hapipah Mohd Ali
  The gastro-protective effects of the aqueous leaf extract of Melastoma malabathricum was investigated against ethanol-induced gastric mucosal injuries in rats. There were four groups of adult sprague dawley rats, consisting of six rats per group. Macroscopically, oral administration of absolute ethanol to rats that had been pre-treated with only distilled water significantly produced extensive lesions of the gastric mucosa. Oral pre-treatment with either 250 mg kg-1 of M. malabathricum extract, 500 mg kg-1 of M. malabathricum extract, or 20 mg kg-1 of omeprazole 60 minutes before administration of absolute ethanol significantly reduced the formation of gastric mucosal injuries. The observed protection was significant and dose dependent in inhibiting ethanol-induced gastric ulcers. Microscopically, rats that had been pre-treated with only distilled water showed marked damage of the gastric mucosa, induced submucosal edema and leucocytes infiltration. However, animals that had been pre-treated with aqueous leaf extracts or omeprazole showed marked reduction of gastric mucosal damage, reduction of oedema and less leucocyte infiltration of submucosal layer. The results indicated that 500 mg kg-1 aqueous leaf extract of M. malabathricum provided the best protection to the gastric mucosa in rats against ethanol-induced gastric ulcers.
  Kek Heng Chua , Suzita Mohd Noor , Ching Hoong Chew and Chin Theam Lim
  Mortality rate in the preterm neonate is believed to be associated with the chronic lung disease (CLD) and CLD is mainly caused by the infections of either Ureaplasma urealyticum or Mycoplasma horminis based on other studies. Therefore in this research, endotracheal aspirates of 57 intubated Malaysian premature neonates were used to study the association between colonization of Ureaplasma urealyticum or Mycoplasma in the respiratory tract of preterm neonates with subsequent development of chronic lung disease using Mycofast® screening kit and nested PCR approaches. Overall, only 1 out of 57 samples was detected to have a mixture of 2 different Mycoplasma species using the later approach. Therefore, we conclude that development of chronic lung disease in Malaysian premature neonates is not due to colonization of Ureaplasma urealyticum or Mycoplasma but other factors.
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