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Articles by Suhaila Mohamed
Total Records ( 2 ) for Suhaila Mohamed
  Kumeshini Sukalingam , Kamsiah Jaarin , Qodriyah Haji Mohd Saad , Suhaila Mohamed and Faizah Othman
  Background and Objective: Oxidative stress is connected with the pathogenesis of cardiovascular diseases. A series of deep-fat frying in dietary cooking oil produce more amount of reactive oxygen species. In this study, repeatedly heated palm oil and ADD-X were studied for its effect on the Blood Pressure (BP), lipid peroxidation and antioxidant parameters. Methodology: Thirty female Sprague-Dawley rats were divided into 5 groups with 6 rats each. All groups of the animals were ovariectomized after anesthetized. Group 1 was fed 2% cholesterol chow (Chol-C), groups 2 and 4, respectively fed 2% cholesterol chow along with 5 and 10 times heated palm oil (5 HPO and 10 HPO). Groups 3 and 5 were respectively given 2% cholesterol chow with 5 HPO and 10 HPO along with ADD-X. Duration of the feeding was 6 months. Systolic, diastolic and mean BP were monitored 4 weeks intervals using a non-invasive method. At the end of the study, blood was collected for oxidative stress and antioxidant parameters. Results: The BP was elevated significantly (p<0.05) in 10 HPO and 5 HPO groups, respectively, where the 10 HPO group viewing higher values. The Increased in BP was significantly lower in ADD-X treated groups. The level of thiobarbituric acid reactive substances (TBARS) was significantly increased in 5 HPO and 10 HPO treated animals and decrease antioxidant parameters compared to Chol-C animals. Consumption of ADD-X reduces TBARS and increase antioxidant enzymes. Conclusion: Repeatedly heated palm oil increases BP, lipid peroxidation and decrease antioxidant enzymes. Supplementation of ADD-X reversed the BP and reduce oxidative stress biomarkers in the post menopausal rat models.
  Samaneh Ghasemi Fard , Fatemeh Tash Shamsabadi , Mozhdeh Emadi , Goh Yong Meng , Kharidah Muhammad and Suhaila Mohamed
  Hair is considered to be a major component of an individual’s general appearance. It is also psychosocial important and patients both men and women with hair loss (alopecia) often deeply suffer. Demand for medications that alter hair growth and appearance has led to a multibillion-dollar industry and thus far few natural effective products are available. For the purpose of ascertaining natural products which possess hair growing activity we looked over onto ethanolic and aqueous extracts of E. cottonii. Hair follicle epithelial stem cells and their contribution to skin healing have attracted particular attention. Oral treatments commenced soon after shaving the dorsal interscapular area of healthy male Sprague-Dawley rats. Microscopic observations of skin were performed. This study showed ethanolic extract of E. cottonii enhanced hair growth by higher proliferative activity. Ethanolic extract of this seaweed increased the rate of wound contraction and epithelization when compared to positive and negative control groups. The ethanolic extract of E. cottonii was approximately 20% more effective than aqueous extraction. The extraction also possesses several antioxidant compounds which may be responsible for the accelerated hair growth and wound healing. We demonstrated for the first time in the present study that this seaweed extracts revealed faster healing and hair growth even when compared with positive control group.
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