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Articles by Srinivas Koduru
Total Records ( 2 ) for Srinivas Koduru
  Srinivas Koduru , F.O. Jimoh , D.S. Grierson and A.J. Afolayan
  In this study two steroid glycosides were isolated from the berries of this plant, which were identified as tomatidine and solasodine by spectroscopic techniques. Antioxidant activities of these compounds were investigated using DPPH, ABTS and reducing power assays. The IC50 confirmed the antioxidant potentials of tomatidine and solasodine. DPPH free radical activity was examined at 30 and 60 min. The highest inhibition was observed when the two compounds were combined, followed by solasodine while tomatidine showed the least inhibition. On the other hand, the activity of ABTS was greater than the DPPH and the activity of the combined compounds was faintly less than solasodine. The activity observed in the reducing power assay was higher in the combined compounds and followed by solasodine and tomatidine. This study has revealed strong antioxidant activity and synergistic effect of the isolated compounds from S. aculeastrum berries.
  Srinivas Koduru , D.S. Grierson and A.J. Afolayan
  Solanum aculeastrum is an important medicinal plant which is used for the treatment of several diseases including cancer in South Africa. The structure and distribution of foliar appendages on the leaves of this plant were examined by scanning electron microscope. Both glandular and non-glandular trichomes were observed, which differed from each other in morphology and location on the leaf. While short-stalked (SST) glandular trichomes were abundant on the adaxial leaf surface, single, multicellular and pointed stellate trichomes (ST) having 13-15 arms, were abundant on the abaxial surface of the leaf, together with long-stalked glandular trichomes (LST). We hypothesize that the bioactive therapeutic compounds secreted by S. aculeastrum are produced in these glandular trichomes.
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