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Articles by Sana Janakat
Total Records ( 2 ) for Sana Janakat
  Abdul-Wahab R. Hamad , Waleed M. Al-Momani , Sana Janakat and Sawsan A. Oran
  Ellagic Acid (EA) is a complex planar molecule which demonstrates a variety of anticarcinogenic activities. Ellagic Acid acts as a scavenger to "bind" cancer-causing chemicals, making them inactive. It also has anti-bacterial, anti-viral properties. The concentration of EA was assessed in serum of twenty healthy volunteers over time interval from 0.15, 0.3, 1, 1.30, 2, 3, 6, 8 and 12 h. The serum concentration-time profile is presented after administration of 40 mg of ellagic acid to 20 healthy volunteers. Isocratic reversed phase liquid chromatographic method was developed for determination of low quantity of Ellagic Acid (EA) on reversed phase Lichrospher 100 RP-18, 5 μm (250 x 4.6 mm i.d) column and using methanol as mobile phase. The eluted EA was detected by UV set at 254 nm. Calibration curve for standard EA is linear with correlation coefficient of 0.9997 for detector response plotted against concentration range from 20-1000 ng/ml. The concentration of ellagic acid (Cmax) was highest in blood one hour (T max) after oral administration. It was 200.15±26.66 ng/ml., the mean serum elimination half-life was about 8.4±1.4 h. More than 50% of ellagic acid boud to plasma protein following oral administration, absorption of ionized ellagic acid occurs in stomach and intestine. Therefore, one capsule three times has drug bioavailability through all day.
  Waleed Al Momani , Sana Janakat and Moawiah Khatatbeh
  Background and Objective: Microbial contamination of table eggs has important consequences to the poultry industry and illness from contaminated eggs is a serious worldwide public health problem. Contaminated eggs and their products increase the risk of illness in humans. The significance of these illnesses can vary from mild symptoms to life-threatening conditions. The purpose of this study was to investigate the foodborne pathogen contamination of table eggs sold in Jordanian markets. Materials and Methods: One hundred eggs were randomly purchased from packed eggs available in the markets, including free-range home eggs, eggs farmed just after cleaning and just before cleaning and delivered to the microbiology lab. The collected swabs were cultured on suitable media and standard microbiological tests were performed to identify the isolated organism. Results: The following bacterial species were isolated from egg shell surfaces: Staphylococcus, Streptococcus spp., Pseudomonas spp., Proteus spp., Klebsiella spp., Escherichia coli, Bacillus spp., Listeria monocytogenes and Salmonella spp. Conclusion: Although serious human pathogens were not prevalent in this study, effective control measurements should nevertheless be applied to prevent human illness.
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