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Articles by Sait Celik
Total Records ( 2 ) for Sait Celik
  Sait Celik and Hatice Akkaya
  This study is conducted in order to investigate the correlation between Superoxide Dismutase (SOD), Total Antioxidant Capacity (TAC) and Catalase (CAT). In this context, TAC, SOD, CAT, cholesterol, triglyceride, HDL and LDL were evaluated in 10 weeks old 20 healthy rats and 20 rats with experimentally-induced diabetes. Average SOD, CAT, TAC, HDL were found to be significantly lower in diabetes group than control group (p<0.05). But cholesterol, triglyceride and LDL were found to be significantly lower in control group than diabetes group (p<0.05). A correlation between SOD, CAT activity and TAC has been established both in control and diabetes group. In the result of the study, lower SOD, CAT and TAC levels were observed in diabetes group when compared to control group. According to the data obtained in this study, it was concluded that SOD, CAT and TAC are capable of serving as a parameter to monitor diabetes of patients with type 1 DM.
  Sait Celik and Ahmet Ozkaya
  This study aimed to determine the protective effects of intraperitoneally administered vitamin E, lipoic acid and linalool on the levels of fatty acid in guinea pig liver and muscle under oxidative stress induced by hydrogen peroxide. While the level of total unsaturated fatty acid in the vitamin E, lipoic acid and linalool groups significantly increased (p<0.01) as compared to the H2O2 group but its level slightly increased (p<0.05) as compared with the control, H2O2+ vitamin E, H2O2+ lipoic acid and H2O2+ linalool groups in liver. The level of polyunsaturated fatty acid (PUFA) in H2O2+ vitamin E, H2O2+ lipoic acid and H2O2+ linalool groups increased in comparison with H2O2, decreased in comparison with vitamin E and lipoic acid groups in both tissues. In muscle, the level of unsaturated fatty acid in the H2O2+ vitamin E, H2O2+ lipoic acid and H2O2+ linalool groups increased in comparison with H2O2 group, but its level in the same groups decreased in comparison with vitamin E, lipoic acid and linalool groups. Vitamin E, lipoic acid and linalool could be used in therapeutic approaches, aimed at limiting the damages from oxidation reactions in unsaturated fatty acids.
 
 
 
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