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Articles by S.S. Mohammadi
Total Records ( 2 ) for S.S. Mohammadi
  S.S. Mohammadi , E. Shahbazian , G. Shoeibi and F. Almassi
  The present study was conducted to evaluate the effect of scalp infiltration with Bupivacaine on hemodynamic responses during early stimulation in craniotomy under general anesthesia. Thirty six patients were prospectively randomized to receive Bupivacaine scalp infiltration (B group) or a saline control (S group) as an adjuvant to general anesthesia using isoflurane in 50% N2O-O2. Mean Arterial Blood Pressure (MAP) and Heart Rate (HR) were recorded as base line, after scalp incision or pin insertion and then every 3 min until 12 min. The measurements were repeated every 5 min till dura was opened. The mean difference between the two groups for HR during scalp incision or pin insertion was significant (p = 0.03). The mean MAP throughout the time intervals of preincision or pin insertion to 12 min postincision and then to dural opening were statistically different between the two groups (p = 0.001). No complications related to the technique of block or drugs were recorded. Scalp infiltration with Bupivacaine as an adjuvant to general anesthesia can provide more stable hemodynamics, as measured by HR and MAP changes during early stimulation in craniotomy.
  A. Mehraien , A. Ghafari and S.S. Mohammadi
  We evaluate the effect of topical application of aprotinin to the heart, pericardia and mediastinum before sternal closure, on early post operative bleeding, blood transfusion requirement and ICU staying time after coronary artery bypass graft surgeries. In a randomized double blinded clinical trial, 128 patients who were scheduled for elective coronary artery bypass graft were allocated into two groups. In group A (aprotinin), patients received 500,000KIU (50 mL) aprotinin and in group S (saline group) the same volume of normal saline was applied. The amount of blood loss collected in chest bottle, the number of pack cells requirement during first 24 h after operation and duration of ICU staying time were recorded. The amount of blood loss in group A (aprotinin) was 451±218 mL compared with 707±269 mL in group S (saline) (p = 0.003). The number of pack cells consumption was 0.5±0.7 units in group A (aprotinin) compared with 1.7±1 units in saline group (p = 0.002). Intensive Care Unit (ICU) staying time was 48.8±13.6 h in group A(aprotinin) and 69.4±16.6 h in saline group (p = 0.001). This study showed that topical application of aprotinin at the end of coronary artery surgeries, significantly reduce postoperative bleeding and blood transfusion requirement during first 24 h after operation and also ICU staying time.
 
 
 
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