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Articles by S.K. Rastogi
Total Records ( 2 ) for S.K. Rastogi
  Quazi S. Haque , Farrukh Jamal and S.K. Rastogi
  Male agricultural workers in the age group of 20-57 years employed in manual pesticide mixing, formulation and spraying at mango orchards at Malihabad and Mal, the mango belt in the vicinity of Lucknow were studied for occupational health risks. A control group belonging to similar socio-economic status and never involved either in agricultural operations or pesticide handling (reference group n = 50) was taken randomly from the same area for comparison purpose. Our findings revealed a high morbidity (76.6%) among the exposed population in contrast to (20%) observed in the reference group. The chief morbidity pertained to neuro symptoms and gastrointestinal problems as a result of occupational exposure to pesticides. Biochemical studies revealed that the acetyl-cholinesterase (AChE) activity in the blood was significantly lowered in the sprayers compared to the levels found in controls (p<0.01). Also, malondialdehyde level was significantly elevated among the sprayers (p<0.01) thereby indicating oxidative stress among the sprayers.
  Mrigakshi Yadav , S.K. Rastogi , Satish Kumar and Malini Pant
  Monitoring anaesthetic depth allows recognizing the extent of physiological stress. Heart is the core organ directly influenced by stress while hematological and biochemical analysis allow quick and accurate diagnosis. This study aimed to evaluate stress on goats subjected to propofol and xylazine-ketamine anaesthesia electrocardiographically, hematologicaly, biochemicaly and by clinical parameters thereby suggesting a suitable anaesthetic for short term surgical interventions. Twelve healthy adult female crossbred goats, aged 2-4 years were randomly allocated to two groups according to the anaesthetics. Electrocardiography (ECG), Oxyhemoglobin (HbO2) saturation, Hematological (Hb concentration, PCV, TEC, TLC, DLC, MCV, MCH and MCHC), blood glucose and clinical parameters (rectal temperature, pulse and respiratory rates) were assessed. The results indicated that after propofol and xylazine-ketamine administration HbO2 decreased (within normal physiological limits after xylazine-ketamine administration), all ECG parameters increased except QRS interval (no change). During propofol anaesthesia rectal temperature, respiratory rate and hematological parameters (except lymphocyte count) decreased while blood glucose concentration and pulse rate increased. During xylazine-ketamine anaesthesia, similar observations were recorded except that pulse rate decreased and MCHC non-significantly increased. Propofol produced favorable effects on cardiovascular system, rectal temperature and pulse rate whereas, xylazine-ketamine exerted more effective anaesthetic effects on respiratory system, blood glucose concentration and hematology suggesting it to be a safer and better choice over propofol for short period anaesthetic requirements in goats. Therefore, it could be suggested for further investigations in clinical conditions.
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