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Articles by S.E.I. Adam
Total Records ( 7 ) for S.E.I. Adam
  E.H. Abdel Gadir , W.S. Abdel Gadir and S.E.I. Adam
  Allium cepa and Allium sativum were fed to male Wistar rats at 2 or 6% of standard diet for 4 weeks. Sodium selenite was also fed to rats at 1ppm and 3 ppm for a similar period. Two percent A. cepa and 2% A. sativum or 1 ppm sodium selenite were not toxic to rats. Impairment of growth and hepatonephropathy were observed in the rats fed diets containing 6% A. cepa and 6% A. sativum or 3 ppm sodium selenite. These changes were correlated with alterations in serum aspartate aminotransferase (AST) alanine aminotransferase, (ALT) and alkaline phosphatase (ALP) activities and total protein, albumin, cholesterol and urea concentrations and hematology.
  I.A. Ibrahim , S.M.A. El Badwi , A.O. Bakhiet , W.S. Abdel Gadir and S.E.I. Adam
  The objective of the present study was to investigate the effects of low levels of dietary Cuminum cyminum seeds and Hibiscus sabdariffa calyces on the growth, organ pathology, haematological and serobiochemical parameters of Bovans chicks. C. cyminum seeds and H. sabdariffa calyces were fed to 7-day-old Bovans chicks at 2 and 10% of the diet for 9 weeks. The 10% H. sabdariffa calyx was toxic but not fatal to chicks and caused reduced body weight gain, inefficient feed utilization, enterohepatotoxicity, anaemia and alterations in serum aspartate aminotransferase and creatine kinase activities and cholesterol, total lipid and uric acid concentrations. These changes were also observed in the chicks fed C. cyminum seed at 10% of the diet and H. sabdariffa calyx at 2% of the diet but were less marked.
  Shama I. Younis and S.E.I. Adam
  We present the first reported study of the effects of feeding Rhanterium epapposum aerial parts at 20, 50, 100 and 200 g kg-1 of standard diet to male Wistar rats for 12 weeks. The criteria of assessment of the plant toxicity were the effects on growth, organs of the body, hematological and serobiochemical parameters of rats. Depression in growth and hepatonephropathy were severe in rats fed diets containing 100 and 200 g kg-1 of R. epapposum aerial parts. These findings were accompanied by macrocytic hypochromic anemia, leukocytosis due to lymphocytosis and alterations of serum concentrations of urea, total protein, globulin and other serum constituents. Toxicity may be frequent in animals that ingest this plant in a dry year. While this plant has traditionally been used in Sudan and other Afro-Asian countries it may show toxic effects in human that result from over-dosage because, in general, there is no standardized dosage system in traditional medical practice.
  E.H. Abdel Gadir , W.S. Abdel Gadir and S.E.I. Adam
  Although diets containing mixtures of 600 mg kg-1 of KBrO3 plus 2% Allium sativum, 600 mg kg-1 KBrO3 plus 2% Allium cepa and 600 mg kg-1 of KBrO3 plus 1 mg kg-1 sodium selenite did not adversely affect the growth of Wistar rats, a significant decrease in body weight gain, hepatonephropathy, desquamation of the intestinal epithelium into the lumen and lymphocytic accumulation in vital organs were observed in the rats fed a diet consisting of 600 mg kg-1 of KBrO3 singly for 4 weeks. These changes associated with macrocytic normochromic anemia were correlated with alterations in serum aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) activities and concentrations of cholesterol, urea and other serum constituents. However, none of the rats died during the 4-week period.
  Einas M. Elhabib , M.M.A. Homeida and S.E.I. Adam
  Cuminum cyminum fruit or Nigella sativa seed, a traditional medicine for treatment of various disorders, was fed to male Wistar rats at 6% of standard rat diet for 4 weeks. A 6% C. cyminum fruit or 6% N. sativa seed diet was not toxic to rats. Depression in growth, hepatotoxicity and nephrotoxicity were observed in rats that had been given paracetamol at 500 mg kg-1 per os for 4 weeks. These findings were accompanied by leucopenia, macrocytic normochromic anemia and alterations of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) activities and concentrations of cholesterol, urea and other serum constituents. Serum bilirubin did not change. In rats given the mixture of paracetamol 500 mg kg-1 plus 6% C. cyminum fruit or 6% N. sativa seed for 4 weeks, the recovery of paracetamol hepatotoxicity was evidenced by increase in body weight, absence of hepatocellular fatty vacuolation and significant improvement of serbiochemical and hematological parameters. There was no evidence of any antinephrotoxic activity of plants used.
  E.H. Abdel Gadir , W.S. Abdel Gadir and S.E.I. Adam
  The toxicity to male Wistar rats of potassium bromate (KBrO3) was investigated. KBrO3 was fed to rats at 75, 150, 600 and 1200 mg kg-1 diet for 4 weeks. The rats fed diets containing 600 and 1200 mg kg-1 of KBrO3 had the lowest growth rate but none of the rats died during the 4 week period. Depression in growth, nephropathy, hepatopathy and lymphocytic infiltration in vital organs were accompanied by anemia, leukopenia and alterations in serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) activities with changes in concentration of urea, cholesterol and other serum constituents. Diet consisting of 150 mg kg-1 of KBrO3 was less toxic to rats.
  Amel O. Bakhiet , Sabna D. Mohammed , Samia, M.A. El Badwi , Warda, S. Abdel Gadir , Abdel-Gadir H.Alkhatim and S.E.I. Adam
  Petroleum ether, ethanolic and water extracts of Petroselinum sativum and Coriandrum sativum were screened for antibacterial activity against one standard gram-positive bacterium (Staphylococcus aureus) and three gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi). Petroleum ether extract from C. sativum in different concentrations (25-100%) did not show any antibacterial activity against the test bacteria while the petroleum ether extract from C. sativum was active against only Pseudomonas aeruginosa. The ethanol extracts of the two plants were active against all test bacteria (S. aureus, E. coli, Ps. aeruginosa and S. typhi), but that from P. sativum was inactive against E. coli. The water extract from P. sativum was active against all bacteria while that from C. sativum was active against S. aureus, Ps. aeruginosa and S. typhi but inactive against E. coli.
 
 
 
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