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Articles by S.B. Oladele
Total Records ( 4 ) for S.B. Oladele
  S.B. Oladele , M. Morou , S.J. Sambo and O.J. Ibu
  Comparative studies of packed cell volume (PCV), haemoglobin (HB), total protein (TP), haemagglutination inhibition (HI) antibodies and rectal temperature (RT) were carried out on a total of 50 pigeons (Columbia livia) that were administered Newcastle disease virus (NDV) Kudu 113 strain through different routes. Fifteen pigeons were administered 0.2 mL each of NDV Kudu 113 strain per os (po), 15 pigeons were inoculated with 0.2 mL of the virus intramuscularly (im), another 15 pigeons were sprayed with about 0.2 mL each of the virus through oculonasal (oc) route, while 15 pigeons served as control. Clinical signs and lesions of Newcastle disease (ND) were observed in some of the infected pigeons. After infection, there was an increase in HI antibodies, reaching the maximum mean values of log2 5.2 ± 0.13, log2 5.3 ± 0.31 and log2 5.0 ± 0.12 in pigeons that were administered NDV Kudu 113 strain through oc, po and im routes, respectively. Similarly, as soon as patent infection was established, the RT continued to rise and attained peak values of 42.31 ± 0.03, 41.94 ± 0.06 and 42.18 ± 0.06 °C in pigeons that were administered the virus through po, im and oc routes, respectively. The values of PCV, HB, TP, HI and RT for the control pigeons were relatively constant, while the corresponding values in the infected pigeons fluctuated widely, depending on the route of administration of the virus. It was concluded that vital blood and body parameters, such as PCV, HB, TP, HI and RT were altered during infection of pigeons with NDV Kudu 113 strain.
  O.J. Ibu , J.O.A. Okoye , S.S. Baba , S.V.O. Soyinka , K.F. Chah , J. Antiabong , D. Eze , E.A. Salihu and S.B. Oladele
  The study was carried out to assess the Haemagglutinin thermostability of Newcastle disease virus isolates obtained from wild birds in three climatically distinct states in central Nigeria. Identification of heat stable ND virus isolates from the locality will provide environmentally friendly thermostable vaccine candidates for rural poultry. The 12 field virus isolates and the 5 vaccine virus strains showed variable degrees of heat stability. Three field isolates each was inactivated in 5 min, three in 10 min and one in 15 min. One isolate was inactivated in 20 min while two and three strains got inactivated in 25 and 30 min respectively. The most thermostable of the field isolates was inactivated in 40 min. A more thermostable clone was subsequently derived from the latter strain as a local vaccine candidate. For the vaccine strains, NDV (I/O) and NDV (K) were inactivated in 20 min while NDV (L) was inactivated in 25 min. The velogenic strain (Herts) was inactivated in 40 min. The two established thermostable strains, NDV4 and NDVI2 were inactivated in 90 min each. The thermostable profile of the field virus strains did not vary with the climatic background of the isolates.
  I.J. Mbuko , W.I. Musa , S. Ibrahim , L. Sa`idu , P.A. Abdu , S.B. Oladele and H.M. Kazeem
  A five year retrospective study (2004-2008) of the prevalence of Gumboro disease (infectious bursal disease, IBD) and other poultry disease diagnosed at the poultry unit of the Ahmadu Bello University Veterinary Teaching Hospital (ABUVTH), Zaria, Kaduna Nigeria was conducted. A prevalence of 7.26% (107 cases) was recorded out of 1473 cases of poultry disease. Gumboro disease occurred throughout the year in Zaria with a high incidence during the festival periods (July-September, October-December and January-March). The outbreaks of IBD were observed to be 1.3 times more likely to occur in pre-rainy season (April-June). Improved breeds of chickens were 5.8 times more likely to suffer from IBD than free range local chickens with broilers being 5.7 times more likely to suffer from the disease than other type of birds followed by layers kept together with cockerels. The prevalence of IBD is influenced by age of birds with an increase in the likelihood of IBD occurring within the age range of 3-5 week. Birds at 5 weeks old were at highest risk. Chickens with one vaccination history against IBD were 8.2 times more likely to suffer from the disease compared to non-vaccinated chickens. This study recommends that poultry farmers should be encourage to improve on farm biosecurity and ensure that their birds are vaccinated at least twice, before 3 and 5 weeks of age (at 1 and 3 or 2 and 4 weeks of age).
  I.W. Musa , P.A. Abdu , A.K.B. Sackey , S.B. Oladele , S. Lawal and I.U. Yakubu
  This report describes an outbreak of an acute, highly lethal, Newcastle Disease (ND) in two broiler flocks that were intensively managed and vaccinated against Newcastle disease. The broiler flocks (325) were four weeks and (450) were six weeks old at the time of the outbreak. Clinical characteristics of the disease included a 100% morbidity, increasing high mortality i.e. 40 birds (day one), 70 birds (day two), 180 (day three) and the entire flocks consisting of 755 birds were lost by the fifth day. Clinical features observed included severe depression, gasping, anorexia, cyanosis and subcutaneous haemorrhages of the legs and shank. Gross lesions seen were severe congestion of skeletal muscles and visceral organs and severe haemorrhages and congestion of the proventriculus, cecal tonsils and trachea, air saculitis with severely congested and pneumonic lungs were observed as well. Ten cloacal swabs from dead and sick birds were tested using a Rapid Newcastle Disease and Avian Influenza Antigen Detection Test Kits. This Chromatographic- immunoassay tested positive for ND and negative for AI confirming the presence of ND viral antigen. Four dead and live birds taken to National Veterinary Research Institute (NVRI) Vom, Nigeria for further confirmation were tested using rapid test kit, haemagglutination inhibition test and viral isolation. These tests were also negative for AI but positive for vvND. Clinical signs and gross lesions of ND and Highly Pathogenic Avian Influenza (HPAI) seem not to be distinguishable in the field. This is likely going to affect disease reporting and actions to be taken. Vaccination against ND should not be totally relied upon especially when birds are not seromonitored pre and post vaccination.
 
 
 
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